Julian P T Higgins
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Explore the profile of Julian P T Higgins including associated specialties, affiliations and a list of published articles.
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229
Citations
87320
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Recent Articles
1.
Vale C, Godolphin P, Fisher D, Higgins J, McAleenan A, Spiga F, et al.
Ann Intern Med
. 2024 Dec;
178(1):59-69.
PMID: 39715559
Background: Reported results of clinical trials assessing higher-dose anticoagulation in patients hospitalized for COVID-19 have been inconsistent. Purpose: To estimate the association of higher- versus lower-dose anticoagulation with clinical outcomes....
2.
Smith K, Boyce N, Chevance A, Chiocchia V, Correll C, Donoghue K, et al.
Br J Psychiatry
. 2024 Dec;
:1-9.
PMID: 39710623
Background: Trace amine-associated receptor 1 (TAAR1) agonists offer a new approach, but there is uncertainty regarding their effects, exact mechanism of action and potential role in treating psychosis. Aims: To...
3.
Hernan M, Sterne J, Higgins J, Shrier I, Hernandez-Diaz S
Epidemiology
. 2024 Nov;
36(1):107-114.
PMID: 39494894
Immortal time may arise in survival analyses when individuals are assigned to treatment strategies based on post-eligibility information or selected based on post-assignment eligibility criteria. Selection based on eligibility criteria...
4.
Davies A, Higgins J
Stat Med
. 2024 Oct;
43(27):5217-5233.
PMID: 39382107
Network meta-analysis (NMA) combines evidence from multiple trials to compare the effectiveness of a set of interventions. In many areas of research, interventions are often complex, made up of multiple...
5.
Davies A, Ades A, Higgins J
Res Synth Methods
. 2024 Oct;
15(6):1072-1093.
PMID: 39357992
Quantitative evidence synthesis methods aim to combine data from multiple medical trials to infer relative effects of different interventions. A challenge arises when trials report continuous outcomes on different measurement...
6.
Salcher-Konrad M, Nguyen M, Savovic J, Higgins J, Naci H
JAMA Netw Open
. 2024 Sep;
7(9):e2436230.
PMID: 39331390
Importance: Randomized clinical trials (RCTs) are widely regarded as the methodological benchmark for assessing clinical efficacy and safety of health interventions. There is growing interest in using nonrandomized studies to...
7.
Vale C, Godolphin P, Fisher D, Horby P, Kosiborod M, Hochman J, et al.
Lancet Diabetes Endocrinol
. 2024 Sep;
12(10):735-747.
PMID: 39250923
Background: Sodium-glucose co-transporter-2 (SGLT2) inhibitors have been proposed as a potential treatment for adults hospitalised with COVID-19, due to their potential anti-inflammatory and endothelial protective effects. Published evidence from randomised...
8.
Thomas K, Dalili M, Cheng H, Dawson S, Donnelly N, Higgins J, et al.
Addiction
. 2024 Aug;
119(11):1904-1922.
PMID: 39111346
Background And Aims: Chronic non-cancer pain (CNCP) is one of the most common causes of disability globally. Opioid prescribing to treat CNCP remains widespread, despite limited evidence of long-term clinical...
9.
Higgins J, Morgan R, Rooney A, Taylor K, Thayer K, Silva R, et al.
Environ Int
. 2024 Mar;
186:108602.
PMID: 38555664
Background: Observational epidemiologic studies provide critical data for the evaluation of the potential effects of environmental, occupational and behavioural exposures on human health. Systematic reviews of these studies play a...
10.
Lunny C, Veroniki A, Higgins J, Dias S, Hutton B, Wright J, et al.
Syst Rev
. 2024 Jan;
13(1):25.
PMID: 38217041
Introduction: Network meta-analyses (NMAs) have gained popularity and grown in number due to their ability to provide estimates of the comparative effectiveness of multiple treatments for the same condition. The...