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Julian Hellmann-Regen

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Articles 60
Citations 663
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Recent Articles
1.
Schneider L, Freiesleben S, van Breukelen G, Wang X, Brosseron F, Heneka M, et al.
Alzheimers Dement . 2025 Jan; 21(2):e14545. PMID: 39868793
Introduction: The beneficial effects of amyloid beta 1-38, or Aβ(1-38), on Alzheimer's disease (AD) progression in humans in vivo remain controversial. We investigated AD patients' cerebrospinal fluid (CSF) Aβ(1-38) and...
2.
Hass S, Liebscher M, Richter A, Fliessbach K, Laske C, Sodenkamp S, et al.
Front Aging Neurosci . 2025 Jan; 16():1451850. PMID: 39777046
Background: In humans, environmental enrichment (EE), as measured by the engagement in a variety of leisure activities, has been associated with larger hippocampal structure and better memory function. The present...
3.
Kulakova E, Graumann L, Cho A, Deuter C, Wolf O, Hellmann-Regen J, et al.
Eur J Psychotraumatol . 2024 Dec; 15(1):2431368. PMID: 39621360
Women with borderline personality disorder (BPD) show increased basal levels of testosterone. We investigated whether salivary testosterone levels in women with BPD were indicative of specific symptoms associated with BPD....
4.
Graumann L, Kulakova E, Cho A, Deuter C, Wolf O, Schell J, et al.
Psychoneuroendocrinology . 2024 Nov; 171():107232. PMID: 39509755
Objective: Borderline personality disorder (BPD) is marked by unstable relationships and fear of abandonment. Earlier studies suggest that patients with BPD are highly sensitive to social exclusion and show deficits...
5.
Bernal J, Menze I, Yakupov R, Peters O, Hellmann-Regen J, Freiesleben S, et al.
Alzheimers Res Ther . 2024 Oct; 16(1):240. PMID: 39465440
Background: For over three decades, the concomitance of cortical neurodegeneration and white matter hyperintensities (WMH) has sparked discussions about their coupled temporal dynamics. Longitudinal studies supporting this hypothesis nonetheless remain...
6.
Kaczmarczyk M, Deuter C, Deus H, Kallidou A, Merz C, Hellmann-Regen J, et al.
Transl Psychiatry . 2024 Oct; 14(1):449. PMID: 39448569
Altered fear conditioning and extinction learning are discussed as key etiological features in anxiety disorders. Women have an increased risk for anxiety disorders and fear conditioning has been shown to...
7.
Dorner M, Seebach K, Heneka M, Menze I, von Kanel R, Euler S, et al.
Diagnostics (Basel) . 2024 May; 14(9). PMID: 38732354
Inferior frontal sulcal hyperintensities (IFSHs) on fluid-attenuated inversion recovery (FLAIR) sequences have been proposed to be indicative of glymphatic dysfunction. Replication studies in large and diverse samples are nonetheless needed...
8.
Rommelspacher H, Bera S, Brommer B, Ward R, Kwiatkowska M, Zygmunt T, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(15):e2314763121. PMID: 38557194
Although sudden sensorineural hearing loss (SSNHL) is a serious condition, there are currently no approved drugs for its treatment. Nevertheless, there is a growing understanding that the cochlear pathologies that...
9.
Kulakova E, Uesekes B, Hellmann-Regen J, Spitzer C, Kuehl L, Otte C, et al.
Psychoneuroendocrinology . 2024 Mar; 164:107026. PMID: 38507869
Background: Adverse childhood experiences (ACE) elevate the risk of both major depressive disorder (MDD) and metabolic diseases. The underlying pathophysiology might include alterations of adipokine levels as a consequence of...
10.
Zierhut M, Bergmann N, Hahne I, Wohlthan J, Kraft J, Braun A, et al.
J Psychiatr Res . 2024 Feb; 171:222-229. PMID: 38309212
Treatment options for social cognition and negative symptoms in schizophrenia spectrum disorders (SSD) remain limited. Oxytocin could be a promising augmentation approach, but the social context influences the effect in...