Julian C Rayner
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Explore the profile of Julian C Rayner including associated specialties, affiliations and a list of published articles.
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155
Citations
6990
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Recent Articles
1.
Dass S, Kundu P, Naskar D, Kanjee U, Ferreira M, Rayner J, et al.
J Infect Dis
. 2025 Mar;
PMID: 40083318
Plasmodium vivax vaccine discovery lags behind P. falciparum due to the absence of a reliable in vitro culture system. We developed a miniature 384-well assay for the evolutionarily related parasite...
2.
Oberstaller J, Xu S, Naskar D, Zhang M, Wang C, Gibbons J, et al.
Science
. 2025 Feb;
387(6734):eadq7347.
PMID: 39913589
Malaria parasites are highly divergent from model eukaryotes. Large-scale genome engineering methods effective in model organisms are frequently inapplicable, and systematic studies of gene function are few. We generated more...
3.
Dutta I, Bishop M, Rayner J, Creavin T, Ahmed S, Clissold H, et al.
Wellcome Open Res
. 2025 Jan;
9:166.
PMID: 39839974
Attending and participating in scientific research meetings and conferences is a key mechanism for researchers to share information and knowledge, build networks, and establish relationships and collaborations to support career...
4.
Pires C, Chawla J, Sollelis L, Oberstaller J, Zhang M, Wang C, et al.
Sci Rep
. 2024 Dec;
14(1):31010.
PMID: 39730700
Successful transmission of Plasmodium falciparum from one person to another relies on the complete intraerythrocytic development of non-pathogenic sexual gametocytes infectious for anopheline mosquitoes. Understanding the genetic factors that regulate...
5.
Kals E, Kals M, Lees R, Introini V, Kemp A, Silvester E, et al.
PLoS Pathog
. 2024 Sep;
20(9):e1012041.
PMID: 39312588
Malaria pathogenesis and parasite multiplication depend on the ability of Plasmodium merozoites to invade human erythrocytes. Invasion is a complex multi-step process involving multiple parasite proteins which can differ between...
6.
Kioko M, Mwangi S, Pance A, Ochola-Oyier L, Kariuki S, Newton C, et al.
Sci Adv
. 2024 Aug;
10(33):eadl2256.
PMID: 39151016
The impact of cerebral malaria on the transcriptional profiles of cerebral tissues is difficult to study using noninvasive approaches. We isolated plasma extracellular vesicles (EVs) from patients with cerebral malaria...
7.
Siegel S, Trimarsanto H, Amato R, Murie K, Taylor A, Sutanto E, et al.
Nat Commun
. 2024 Aug;
15(1):6757.
PMID: 39117628
Challenges in classifying recurrent Plasmodium vivax infections constrain surveillance of antimalarial efficacy and transmission. Recurrent infections may arise from activation of dormant liver stages (relapse), blood-stage treatment failure (recrudescence) or...
8.
Frischknecht F, Rayner J, Waters A
Trends Parasitol
. 2024 Jul;
40(8):657-659.
PMID: 39025766
In 2004 the first annual BioMalPar meeting was held at EMBL Heidelberg, bringing together researchers from around the world with the goal of building connections between malaria research groups in...
9.
Kariuki S, Gilchrist J, Uyoga S, Macharia A, Makale J, Rayner J, et al.
J Infect Dis
. 2024 Jul;
231(1):e10-e16.
PMID: 38979599
Background: The Dantu blood group variant protects against Plasmodium falciparum infections, but its wider consequences have not been previously explored. Here, we investigate the impact of Dantu on susceptibility to...
10.
Charneau S, Oliveira L, Zenonos Z, Hopp C, Bastos I, Loew D, et al.
Sci Rep
. 2024 May;
14(1):11242.
PMID: 38755230
The interaction of Plasmodium falciparum-infected red blood cells (iRBCs) with the vascular endothelium plays a crucial role in malaria pathology and disease. KAHRP is an exported P. falciparum protein involved...