Julia Timar
Overview
Explore the profile of Julia Timar including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
19
Citations
137
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0
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Recent Articles
1.
Striking Neurochemical and Behavioral Differences in the Mode of Action of Selegiline and Rasagiline
Harsing Jr L, Timar J, Miklya I
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37686140
Selegiline and rasagiline are two selective monoamine oxidase B (MAO-B) inhibitors used in the treatment of Parkinson's disease. In their clinical application, however, differences in L-dopa-sparing potencies have been observed....
2.
Szepesy J, Humli V, Farkas J, Miklya I, Timar J, Tabi T, et al.
Int J Mol Sci
. 2021 Apr;
22(6).
PMID: 33799684
Age-related hearing loss (ARHL), a sensorineural hearing loss of multifactorial origin, increases its prevalence in aging societies. Besides hearing aids and cochlear implants, there is no FDA approved efficient pharmacotherapy...
3.
Furst S, Zadori Z, Zador F, Kiraly K, Balogh M, Laszlo S, et al.
Molecules
. 2020 May;
25(11).
PMID: 32466522
There is growing evidence on the role of peripheral µ-opioid receptors (MORs) in analgesia and analgesic tolerance. Opioid analgesics are the mainstay in the management of moderate to severe pain,...
4.
Knoll J, Zelena D, Timar J, Baghy K, Mervai Z, Miklya I
Behav Brain Res
. 2019 Oct;
378:112290.
PMID: 31610214
Pharmaceutically available enhancer selegiline/(-)-deprenyl (DEP) in the clinically used dose shows antidepressant effect, but nothing is known about this effect in enhancer dose, and its effect on co-morbid anxiety. Moreover,...
5.
Zadori Z, Toth V, Feher A, Al-Khrasani M, Puskar Z, Kozsurek M, et al.
J Pharmacol Exp Ther
. 2016 Jul;
358(3):483-91.
PMID: 27418171
It has been hypothesized that α2-adrenoceptors (α2-ARs) may be involved in the pathomechanism of colitis; however, the results are conflicting because both aggravation and amelioration of colonic inflammation have been...
6.
Harsing Jr L, Timar J, Szabo G, Udvari S, Nagy K, Marko B, et al.
Curr Pharm Des
. 2015 Jan;
21(17):2291-303.
PMID: 25578890
We have synthesized a novel series of N-substituted sarcosines, analogues of NFPS (N-[3-(biphenyl-4- yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine), as type-1 glycine transporter (GlyT-1) inhibitors. Several compounds incorporated a diazine ring inhibited recombinant hGlyT-1b expressed...
7.
Fodor A, Timar J, Zelena D
Life Sci
. 2014 Apr;
104(1-2):1-8.
PMID: 24746901
Opioids are among the world's oldest known drugs used mostly for pain relief, but recreational use is also widespread. A particularly important problem is opioid exposure in females, as their...
8.
Sobor M, Timar J, Riba P, Kiraly K, Al-Khrasani M, Gyarmati Z, et al.
Neuropsychopharmacol Hung
. 2014 Jan;
15(4):239-51.
PMID: 24380965
Unlabelled: Opioids impair the maternal behaviour of experimental animals. The effect of morphine on maternal behaviour in rat dams treated chronically with morphine during the whole pregnancy and lactation has...
9.
Varga J, Klausz B, Domokos A, Kalman S, Pakaski M, Szucs S, et al.
Brain Res Bull
. 2013 Nov;
100:6-13.
PMID: 24177174
Alzheimer's disease (AD) is the most common form of dementia in the elderly. For more effective therapy early diagnostic markers could be beneficial. Therefore we compared one year old rats...
10.
Al-Khrasani M, Lacko E, Riba P, Kiraly K, Sobor M, Timar J, et al.
Brain Res Bull
. 2011 Nov;
87(2-3):238-43.
PMID: 22079588
This study describes the antinociceptive effects of μ-opioid agonists, d-Ala(2),N-Me-Phe(4),Gly(5)-ol-enkephalin (DAMGO) and morphine in a model of rat visceral pain in which nociceptive responses were triggered by 2% acetic acid...