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Julia Luthardt

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Articles 38
Citations 616
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Recent Articles
21.
Zientek F, Winter K, Muller A, Rullmann M, Luthardt J, Becker G, et al.
Eur J Neurosci . 2016 Aug; 44(7):2460-2466. PMID: 27519298
There is evidence that temperamental factors are associated with obesity; however, the biological mechanism of such association remains elusive. We aimed to investigate a possible association between serotonin transmission and...
22.
Hankir M, Kranz M, Gnad T, Weiner J, Wagner S, Deuther-Conrad W, et al.
EMBO Mol Med . 2016 Jun; 8(7):796-812. PMID: 27247380
Phosphodiesterase type 10A (PDE10A) is highly enriched in striatum and is under evaluation as a drug target for several psychiatric/neurodegenerative diseases. Preclinical studies implicate PDE10A in the regulation of energy...
23.
Hinderberger P, Rullmann M, Drabe M, Luthardt J, Becker G, Bluher M, et al.
Neuropharmacology . 2016 Apr; 110(Pt A):530-536. PMID: 27108933
Background: Serotonin (5-HT) and its neurotrophic support system, specifically brain-derived neurotrophic factor (BDNF), are thought to modulate energy homeostasis and susceptibility to obesity. Moreover, a polymorphism (5-HTTLPR) in the serotonin...
24.
Tiepolt S, Hesse S, Patt M, Luthardt J, Schroeter M, Hoffmann K, et al.
Eur J Nucl Med Mol Imaging . 2016 Mar; 43(9):1700-9. PMID: 27026271
Purpose: [(18)F]FDG is a commonly used neuronal injury biomarker for early and differential diagnosis of dementia. Typically, the blood supply to the brain is closely coupled to glucose consumption. Early...
25.
Tuszynski T, Rullmann M, Luthardt J, Butzke D, Tiepolt S, Gertz H, et al.
Eur J Nucl Med Mol Imaging . 2016 Jan; 43(6):1077-87. PMID: 26739328
Introduction: For regional quantification of nuclear brain imaging data, defining volumes of interest (VOIs) by hand is still the gold standard. As this procedure is time-consuming and operator-dependent, a variety...
26.
Hesse S, Rullmann M, Luthardt J, Winter K, Hankir M, Becker G, et al.
Eur J Nucl Med Mol Imaging . 2015 Nov; 43(6):1096-104. PMID: 26577939
Purpose: The role of the central serotonin (5-hydroxytryptamine, 5-HT) system in feeding has been extensively studied in animals with the 5-HT family of transporters (5-HTT) being identified as key molecules...
27.
Rullmann M, Dukart J, Hoffmann K, Luthardt J, Tiepolt S, Patt M, et al.
J Nucl Med . 2015 Nov; 57(2):198-203. PMID: 26541776
Unlabelled: Neocortical atrophy reduces PET signal intensity, potentially affecting the diagnostic efficacy of β-amyloid (Aβ) brain PET imaging. This study investigated whether partial-volume effect correction (PVEC), adjusting for this atrophy...
28.
Sabri O, Becker G, Meyer P, Hesse S, Wilke S, Graef S, et al.
Neuroimage . 2015 Jun; 118:199-208. PMID: 26037057
α4β2* nicotinic receptors (α4β2* nAChRs) could provide a biomarker in neuropsychiatric disorders (e.g., Alzheimer's and Parkinson's diseases, depressive disorders, and nicotine addiction). However, there is a lack of α4β2* nAChR...
29.
Hesse S, Moeller F, Petroff D, Lobsien D, Luthardt J, Regenthal R, et al.
Eur J Nucl Med Mol Imaging . 2014 Feb; 41(5):827-35. PMID: 24562640
Purpose: Modulation of the immune system by the CNS may involve serotonergic regulation via the brain serotonin transporters (SERT). This regulation may be disturbed in patients with CNS disorders including...
30.
Becker G, Ichise M, Barthel H, Luthardt J, Patt M, Seese A, et al.
J Nucl Med . 2013 Mar; 54(5):723-31. PMID: 23471310
Unlabelled: (18)F-florbetaben is a novel (18)F-labeled tracer for PET imaging of β-amyloid deposits in the human brain. We evaluated the kinetic model-based approaches to the quantification of β-amyloid binding in...