Julia Knockel
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Explore the profile of Julia Knockel including associated specialties, affiliations and a list of published articles.
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10
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75
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Recent Articles
1.
Knockel J, Dundas K, Yang A, Galaway F, Metcalf T, van Gemert G, et al.
Mol Cell Proteomics
. 2021 Jan;
20:100038.
PMID: 33515807
Sporozoites are a motile form of malaria-causing Plasmodium falciparum parasites that migrate from the site of transmission in the dermis through the bloodstream to invade hepatocytes. Sporozoites interact with many...
2.
Molina-Cruz A, Lehmann T, Knockel J
Trends Parasitol
. 2013 Oct;
29(11):530-7.
PMID: 24140295
Human malaria is known to be transmitted strictly by anopheline mosquitoes. Culicine mosquitoes such as Aedes spp. and Culex spp. are important vectors of other human pathogens including viruses and...
3.
Knockel J, Molina-Cruz A, Fischer E, Muratova O, Haile A, Barillas-Mury C, et al.
PLoS One
. 2013 May;
8(5):e63387.
PMID: 23658824
Although Anopheles mosquitoes are the vectors for human Plasmodium spp., there are also other mosquito species-among them culicines (Culex spp., Aedes spp.)-present in malaria-endemic areas. Culicine mosquitoes transmit arboviruses and...
4.
Knockel J, Muller I, Butzloff S, Bergmann B, Walter R, Wrenger C
Biochem J
. 2012 Jan;
443(2):397-405.
PMID: 22242896
The malaria parasite Plasmodium falciparum is able to synthesize de novo PLP (pyridoxal 5'-phosphate), the active form of vitamin B6. In the present study, we have shown that the de...
5.
Muller I, Knockel J, Eschbach M, Bergmann B, Walter R, Wrenger C
Cell Microbiol
. 2010 Jan;
12(5):677-91.
PMID: 20070315
As an intracellular proliferating parasite, Plasmodium falciparum exploits the human host to acquire nutrients. However, nutrients such as nucleotides and cofactors are mostly phosphorylated in the host cell cytosol and...
6.
Knockel J, Jordanova R, Muller I, Wrenger C, Groves M
Biochim Biophys Acta
. 2009 Mar;
1790(5):347-50.
PMID: 19272411
Background: Vitamin B6 synthesis requires a functional Pdx1 assembly that is dodecameric in vivo. We have previously shown that mutation of a catalytic lysine in the plasmodial Pdx1 protein results...
7.
Muller I, Wu F, Bergmann B, Knockel J, Walter R, Gehring H, et al.
PLoS One
. 2009 Feb;
4(2):e4406.
PMID: 19197387
The human malaria parasite Plasmodium falciparum is able to synthesize de novo pyridoxal 5-phosphate (PLP), a crucial cofactor, during erythrocytic schizogony. However, the parasite possesses additionally a pyridoxine/pyridoxal kinase (PdxK)...
8.
Muller I, Knockel J, Groves M, Jordanova R, Ealick S, Walter R, et al.
PLoS One
. 2008 Mar;
3(3):e1815.
PMID: 18350152
Background: Plants, fungi, bacteria and the apicomplexan parasite Plasmodium falciparum are able to synthesize vitamin B6 de novo, whereas mammals depend upon the uptake of this essential nutrient from their...
9.
Knockel J, Bergmann B, Muller I, Rathaur S, Walter R, Wrenger C
Mol Biochem Parasitol
. 2007 Dec;
157(2):241-3.
PMID: 18067979
Thiamine pyrophosphate (TPP), the active form of vitamin B1, is an essential cofactor for several enzymes. Humans depend exclusively on the uptake of vitamin B1, whereas bacteria, plants, fungi and...
10.
Knockel J, Muller I, Bergmann B, Walter R, Wrenger C
Mol Biochem Parasitol
. 2007 Jan;
152(1):108-11.
PMID: 17222923
No abstract available.