Julia Kiyan
Overview
Explore the profile of Julia Kiyan including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
133
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Recent Articles
1.
Dangers M, Kiyan J, Grote K, Schieffer B, Haller H, Dumler I
J Vasc Res
. 2010 Feb;
47(5):432-40.
PMID: 20145416
Background: The growth-promoting effect of mechanical stress on vascular smooth muscle cells (VSMC) has been implicated in the progress of cardiovascular diseases related to elevated blood pressure. The underlying molecular...
2.
Jerke U, Tkachuk S, Kiyan J, Stepanova V, Kusch A, Hinz M, et al.
PLoS One
. 2009 Dec;
4(12):e8302.
PMID: 20011528
Background: Members of the signal transducer and activator of transcription (Stat) family of transcription factors traverse the nuclear membrane through a specialized structure, called the nuclear pore complex (NPC), which...
3.
Kiyan J, Smith G, Haller H, Dumler I
Biochem J
. 2009 Aug;
423(3):343-51.
PMID: 19691446
The cholesterol-enriched membrane microdomains lipid rafts play a key role in cell activation by recruiting and excluding specific signalling components of cell-surface receptors upon receptor engagement. Our previous studies have...
4.
Fuhrman B, Gantman A, Khateeb J, Volkova N, Horke S, Kiyan J, et al.
Cardiovasc Res
. 2009 Jun;
84(1):145-54.
PMID: 19497963
Aims: We have recently shown that urokinase plasminogen activator (uPA) increases oxidative stress (OS), cholesterol biosynthesis, and paraoxonase 2 (PON2) expression in macrophages via binding to its receptor, the uPAR....
5.
Kiyan J, Haller H, Dumler I
Exp Cell Res
. 2009 Jan;
315(6):1029-39.
PMID: 19133257
The urokinase (uPA)/urokinase receptor (uPAR) multifunctional system is an important mediator of functional behaviour of human vascular smooth muscle cells (VSMC). uPAR associates with platelet-derived growth factor receptor beta (PDGFR-beta),...
6.
Gueler F, Rong S, Mengel M, Park J, Kiyan J, Kirsch T, et al.
J Immunol
. 2008 Jul;
181(2):1179-89.
PMID: 18606671
Central mechanisms leading to ischemia induced allograft rejection are apoptosis and inflammation, processes highly regulated by the urokinase-type plasminogen activator (uPA) and its specific receptor (uPAR). Recently, up-regulation of uPA...
7.
Tkachuk N, Kiyan J, Tkachuk S, Kiyan R, Shushakova N, Haller H, et al.
Biochem J
. 2008 Jun;
415(2):265-73.
PMID: 18564064
Deregulated apoptosis of MCs (mesangial cells) is associated with a number of kidney diseases including end-stage diabetic nephropathy. Cell death by apoptosis is a tightly orchestrated event, whose mechanisms are...
8.
Kiyan J, Kusch A, Tkachuk S, Kramer J, Haller H, Dietz R, et al.
Atherosclerosis
. 2007 Feb;
195(2):254-61.
PMID: 17275828
The urokinase (uPA)/urokinase receptor (uPAR) multifunctional system is an important mediator of migration and proliferation of vascular smooth muscle cells (VSMC). However, whether uPA/uPAR-directed mechanisms are involved in the beneficial...
9.
Kiyan J, Kiyan R, Haller H, Dumler I
EMBO J
. 2005 May;
24(10):1787-97.
PMID: 15889147
Urokinase (uPA)-induced signaling in human vascular smooth muscle cells (VSMC) elicits important cellular functional responses, such as cell migration and proliferation. However, how intracellular signaling is linked to glycolipid-anchored uPA...