Julia C Cronin
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Explore the profile of Julia C Cronin including associated specialties, affiliations and a list of published articles.
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10
Citations
562
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Recent Articles
1.
Nordlinger A, Dror S, Elkahloun A, Del Rio J, Stubbs E, Golan T, et al.
J Invest Dermatol
. 2018 Apr;
138(10):2216-2223.
PMID: 29679610
Melanoma, a melanocyte origin neoplasm, is the most lethal type of skin cancer, and incidence is increasing. Several familial and somatic mutations have been identified in the gene encoding the...
2.
Cronin J, Loftus S, Baxter L, Swatkoski S, Gucek M, Pavan W
PLoS One
. 2018 Jan;
13(1):e0190834.
PMID: 29315345
The transcription factor SOX10 plays an important role in vertebrate neural crest development, including the establishment and maintenance of the melanocyte lineage. SOX10 is also highly expressed in melanoma tumors,...
3.
Loftus S, Baxter L, Cronin J, Fufa T, Pavan W
Pigment Cell Melanoma Res
. 2017 Feb;
30(3):339-352.
PMID: 28168807
Hypoxia and HIF1α signaling direct tissue-specific gene responses regulating tumor progression, invasion, and metastasis. By integrating HIF1α knockdown and hypoxia-induced gene expression changes, this study identifies a melanocyte-specific, HIF1α-dependent/hypoxia-responsive gene...
4.
Hwang H, Baxter L, Loftus S, Cronin J, Trivedi N, Borate B, et al.
Pigment Cell Melanoma Res
. 2014 Apr;
27(5):777-87.
PMID: 24767210
The complex genetic changes underlying metastatic melanoma need to be deciphered to develop new and effective therapeutics. Previously, genome-wide microarray analyses of human melanoma identified two reciprocal gene expression programs,...
5.
Cronin J, Watkins-Chow D, Incao A, Hasskamp J, Schonewolf N, Aoude L, et al.
Cancer Res
. 2013 Aug;
73(18):5709-18.
PMID: 23913827
The transcription factor SOX10 is essential for survival and proper differentiation of neural crest cell lineages, where it plays an important role in the generation and maintenance of melanocytes. SOX10...
6.
Prasad M, Reed X, Gorkin D, Cronin J, McAdow A, Chain K, et al.
BMC Dev Biol
. 2011 Jun;
11:40.
PMID: 21672228
Background: The ERBB3 gene is essential for the proper development of the neural crest (NC) and its derivative populations such as Schwann cells. As with all cell fate decisions, transcriptional...
7.
Prickett T, Agrawal N, Wei X, Yates K, Lin J, Wunderlich J, et al.
Nat Genet
. 2009 Sep;
41(10):1127-32.
PMID: 19718025
Tyrosine phosphorylation is important in signaling pathways underlying tumorigenesis. We performed a mutational analysis of the protein tyrosine kinase (PTK) gene family in cutaneous metastatic melanoma. We identified 30 somatic...
8.
Cronin J, Wunderlich J, Loftus S, Prickett T, Wei X, Ridd K, et al.
Pigment Cell Melanoma Res
. 2009 May;
22(4):435-44.
PMID: 19422606
Microphthalmia-associated transcription factor (MITF) is involved in melanocyte cell development, pigmentation and neoplasia. To determine whether MITF is somatically mutated in melanoma, we compared the sequence of MITF from primary...
9.
Palavalli L, Prickett T, Wunderlich J, Wei X, Burrell A, Porter-Gill P, et al.
Nat Genet
. 2009 Mar;
41(5):518-20.
PMID: 19330028
A mutational analysis of the matrix metalloproteinase (MMP) gene family in human melanoma identified somatic mutations in 23% of melanomas. Five mutations in one of the most commonly mutated genes,...
10.
Solomon D, Kim J, Cronin J, Sibenaller Z, Ryken T, Rosenberg S, et al.
Cancer Res
. 2008 Dec;
68(24):10300-6.
PMID: 19074898
An additional tumor suppressor gene on chromosome 9p telomeric to the CDKN2A/B locus has long been postulated to exist. Using Affymetrix 250K single nucleotide polymorphism arrays to screen for copy...