Julia A Sharp
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Explore the profile of Julia A Sharp including associated specialties, affiliations and a list of published articles.
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9
Citations
142
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Recent Articles
1.
Cranmer K, Pant M, Quesnel S, Sharp J
Pathogens
. 2024 Jan;
13(1).
PMID: 38251333
is a significant human pathogen with a formidable propensity for antibiotic resistance. Worldwide, it is the leading cause of skin and soft tissue infections (SSTI), septic arthritis, osteomyelitis, and infective...
2.
Sage M, Cranmer K, Semeraro M, Ma S, Galkina E, Tran Y, et al.
PLoS One
. 2022 Mar;
17(3):e0265774.
PMID: 35324969
Staphylococcus aureus employs a multitude of immune-evasive tactics to circumvent host defenses including the complement system, a component of innate immunity central to controlling bacterial infections. With antibiotic resistance becoming...
3.
Burket J, Pickle J, Rusk A, Haynes B, Sharp J, Deutsch S
Prog Neuropsychopharmacol Biol Psychiatry
. 2020 Jan;
99:109869.
PMID: 31962186
Stress reactivity and glucocorticoid signaling alterations are reported in mouse models of autism spectrum disorder (ASD). BALB/c mice display decreased locomotor activity in the presence of stimulus mice and spend...
4.
Sharp J, Hair P, Pallera H, Kumar P, Mauriello C, Nyalwidhe J, et al.
PLoS One
. 2015 Jul;
10(7):e0132446.
PMID: 26196285
The complement system has been increasingly recognized to play a pivotal role in a variety of inflammatory and autoimmune diseases. Consequently, therapeutic modulators of the classical, lectin and alternative pathways...
5.
Sharp J, Whitley P, Cunnion K, Krishna N
Front Immunol
. 2014 Sep;
5:406.
PMID: 25202312
The classical pathway of complement plays multiple physiological roles including modulating immunological effectors initiated by adaptive immune responses and an essential homeostatic role in the clearance of damaged self-antigens. However,...
6.
Shah T, Mauriello C, Hair P, Sharp J, Kumar P, Lattanzio F, et al.
Transfusion
. 2014 May;
54(11):2892-900.
PMID: 24806146
Background: Prevention of acute hemolytic transfusion reactions is a worldwide concern. The objective of this study was to develop a simple rat model of complement-mediated acute intravascular hemolysis. Study Design...
7.
Mauriello C, Pallera H, Sharp J, Woltmann Jr J, Qian S, Hair P, et al.
Mol Immunol
. 2012 Aug;
53(1-2):132-9.
PMID: 22906481
Previous experiments from our laboratories have identified peptides derived from the human astrovirus coat protein (CP) that bind C1q and mannose binding lectin (MBL) inhibiting activation of the classical and...
8.
Sharp J, Echague C, Hair P, Ward M, Nyalwidhe J, Geoghegan J, et al.
PLoS One
. 2012 Jun;
7(5):e38407.
PMID: 22675461
Similar to other highly successful invasive bacterial pathogens, Staphylococcus aureus recruits the complement regulatory protein factor H (fH) to its surface to inhibit the alternative pathway of complement. Here, we...
9.
Sharp J, Cunnion K
Mol Immunol
. 2010 Dec;
48(4):683-90.
PMID: 21163532
Staphylococcus aureus is a significant human pathogen that causes skin-structure, invasive, and hospital-associated infections worldwide. The complement system is vital to innate defense against many bacterial infections. As shown with...