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Juehua Jing

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Articles 100
Citations 481
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Recent Articles
1.
Hu Z, Wang C, Wang C, He J, Yan Y, Xu Z, et al.
Sci Rep . 2025 Mar; 15(1):8992. PMID: 40089639
To explore the therapeutic efficacy of L-glutamine (L-Gln) on pathological progression and clinical symptoms of osteoarthritis (OA), and compare with glucosamine sulfate (GS), and celecoxib (CXB). Rats were administered sodium...
2.
Ye J, Shan F, Xu X, Liang C, Zhang N, Hu H, et al.
J Neuroinflammation . 2025 Mar; 22(1):77. PMID: 40075472
Background: Recent studies have confirmed the critical role of neonatal microglia in wound healing and axonal regeneration following spinal cord injury (SCI). However, the limited migration of microglia to the...
3.
Zhao S, Tian D, Huang F, Wang L, Cheng J, He Z, et al.
Cancer Cell Int . 2025 Jan; 25(1):29. PMID: 39885569
Osteosarcoma (OS) is a commonly observed malignant tumor in orthopedics that has a very poor prognosis. The endosomal sorting complex required for transport (ESCRT) is important for the development and...
4.
Ma Z, Meng C, Wang X, Zhao Y, Wang J, Chen Y, et al.
Cell Biosci . 2025 Jan; 15(1):11. PMID: 39881390
Background: Myelin-laden foamy macrophages accumulate extensively in the lesion epicenter, exhibiting characteristics of autophagolysosomal dysfunction, which leads to prolonged inflammatory responses after spinal cord injury (SCI). Trehalose, known for its...
5.
Ouyang F, Zheng M, Li J, Huang J, Ye J, Wang J, et al.
Sci Rep . 2025 Jan; 15(1):2867. PMID: 39843796
Excessive iron deposition can lead to ferroptosis, a form of iron-dependent cell death detrimental to neuronal survival. Microglia have been identified as having a high capacity for iron deposition, yet...
6.
Zhao Y, Lu Z, Song X, Xie H, Xiao X, Wang G, et al.
Pharmacol Res . 2025 Jan; 212:107576. PMID: 39755132
Biased µ-opioid receptor (MOR) agonists enhance pain relief by selectively activating G protein-coupled receptor signaling and minimizing β-arrestin-2 activation, resulting in fewer side effects. This multicenter Phase II/III trial evaluated...
7.
Yu H, Ding C, Hu Z, Liu Q, Gu X, He J, et al.
Sci Rep . 2024 Dec; 14(1):31901. PMID: 39738316
The imbalance in the proportion of M1/M2 macrophage polarization is a crucial contributor to the persistent progression of osteoarthritis (OA). This study aimed to evaluate the effects of low-dose biocompatible...
8.
Luo D, Zheng L, Ding M, Yu D, Chen T, Zheng K, et al.
J Thromb Haemost . 2024 Dec; 23(3):888-902. PMID: 39709053
Background: Hemophilic arthropathy (HA) is a joint disease characterized by local iron overload stemming from erythrocyte rupture and closely linked to synovial lesions. However, the precise molecular characteristics of clinical...
9.
Li J, Zheng M, Ouyang F, Ye J, Huang J, Zhao Y, et al.
CNS Neurosci Ther . 2024 Dec; 30(12):e70181. PMID: 39697159
Background: Effective clearance of lipid-rich debris by macrophages is critical for neural repair and regeneration after spinal cord injury (SCI). Interleukin-3 (IL-3) has been implicated in programming microglia to cluster...
10.
Wang T, Shen Q, Liu Y, Zhao S, Cheng J, Tang Z, et al.
World Neurosurg . 2024 Nov; 194:123448. PMID: 39577624
Objective: The purpose of this study was to determine the efficacy and safety of combined intravenous and topical use of tranexamic acid (TXA) in patients undergoing separation surgery for thoracolumbar...