Jue Zeng
Overview
Explore the profile of Jue Zeng including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
924
Followers
0
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Recent Articles
11.
Wang T, Zeng J, Lowe C, Sellers R, Salama S, Yang M, et al.
Proc Natl Acad Sci U S A
. 2007 Nov;
104(47):18613-8.
PMID: 18003932
The evolutionary forces that establish and hone target gene networks of transcription factors are largely unknown. Transposition of retroelements may play a role, but its global importance, beyond a few...
12.
Papageorgio C, Brachmann R, Zeng J, Culverhouse R, Zhang W, Mcleod H
Int J Oncol
. 2007 Oct;
31(5):1205-11.
PMID: 17912449
The tumor suppressor protein p53 is a transcription factor that is frequently mutated in human cancers. In response to DNA damage, unmutated or wild-type (wt) p53 protein is stabilized and...
13.
Danziger S, Zeng J, Wang Y, Brachmann R, Lathrop R
Bioinformatics
. 2007 Jul;
23(13):i104-14.
PMID: 17646286
Many biomedical projects would benefit from reducing the time and expense of in vitro experimentation by using computer models for in silico predictions. These models may help determine which expensive...
14.
Danziger S, Swamidass S, Zeng J, Dearth L, Lu Q, Chen J, et al.
IEEE/ACM Trans Comput Biol Bioinform
. 2006 Oct;
3(2):114-25.
PMID: 17048398
Many biomedical problems relate to mutant functional properties across a sequence space of interest, e.g., flu, cancer, and HIV. Detailed knowledge of mutant properties and function improves medical treatment and...
15.
Dearth L, Qian H, Wang T, Baroni T, Zeng J, Chen S, et al.
Carcinogenesis
. 2006 Jul;
28(2):289-98.
PMID: 16861262
Over 1000 different mutants of the tumor suppressor protein p53 with one amino acid change in the core domain have been reported in human cancers. In mouse knock-in models, two...
16.
Neuburger P, Saville K, Zeng J, Smyth K, Belote J
Genetics
. 2006 May;
173(3):1377-87.
PMID: 16648584
Two dominant temperature-sensitive (DTS) lethal mutants of Drosophila melanogaster are Pros26(1) and Prosbeta2(1), previously known as DTS5 and DTS7. Heterozygotes for either mutant die as pupae when raised at 29...
17.
Baroni T, Wang T, Qian H, Dearth L, Truong L, Zeng J, et al.
Proc Natl Acad Sci U S A
. 2004 Mar;
101(14):4930-5.
PMID: 15037740
The transcription factor and tumor suppressor protein p53 is frequently inactivated in human cancers. In many cases, p53 gene mutations result in high levels of inactive, full-length p53 protein with...