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Judit Kun

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Articles 6
Citations 497
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Recent Articles
1.
Kardos J, Nyiri M, Moussong E, Wien F, Molnar T, Murvai N, et al.
Protein Sci . 2025 Feb; 34(3):e70066. PMID: 39968955
Protein aggregation and amyloid formation are linked to numerous degenerative diseases, such as Alzheimer's or Parkinson's disease. Additionally, protein aggregation plays a crucial role in various biological processes, such as...
2.
Burke C, Mark K, Kun J, Beauchemin K, Supattapone S
PLoS Pathog . 2024 Jan; 20(1):e1011919. PMID: 38190351
[This corrects the article DOI: 10.1371/journal.ppat.1008581.].
3.
Bulyaki E, Kun J, Molnar T, Papp A, Micsonai A, Vadaszi H, et al.
Biology (Basel) . 2021 Nov; 10(11). PMID: 34827190
β-microglobulin (β2m), the light chain of the MHC-I complex, is associated with dialysis-related amyloidosis (DRA). Recently, a hereditary systemic amyloidosis was discovered, caused by a naturally occurring D76N β2m variant,...
4.
Kovacs R, Vadaszi H, Bulyaki E, Torok G, Toth V, Matyas D, et al.
Front Immunol . 2021 Feb; 11:599771. PMID: 33628204
Elements of the immune system particularly that of innate immunity, play important roles beyond their traditional tasks in host defense, including manifold roles in the nervous system. Complement-mediated synaptic pruning...
5.
Burke C, Mark K, Kun J, Beauchemin K, Supattapone S
PLoS Pathog . 2020 May; 16(5):e1008581. PMID: 32421750
Prions are unorthodox infectious agents that replicate by templating misfolded conformations of a host-encoded glycoprotein, collectively termed PrPSc. Prion diseases are invariably fatal and currently incurable, but oral drugs that...
6.
Micsonai A, Wien F, Bulyaki E, Kun J, Moussong E, Lee Y, et al.
Nucleic Acids Res . 2018 Jun; 46(W1):W315-W322. PMID: 29893907
Circular dichroism (CD) spectroscopy is a widely used method to study the protein secondary structure. However, for decades, the general opinion was that the correct estimation of β-sheet content is...
7.
Gyorffy B, Kun J, Torok G, Bulyaki E, Borhegyi Z, Gulyassy P, et al.
Proc Natl Acad Sci U S A . 2018 May; 115(24):6303-6308. PMID: 29844190
C1q, a member of the immune complement cascade, is implicated in the selective pruning of synapses by microglial phagocytosis. C1q-mediated synapse elimination has been shown to occur during brain development,...