Jubie Selvaraj
Overview
Explore the profile of Jubie Selvaraj including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
50
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Recent Articles
1.
Ramakrishnan B, Mr J, Thangavelu P, M E, Natarajan J, Selvaraj J
Curr Drug Res Rev
. 2025 Mar;
PMID: 40051358
Today's pharmaceutical products are seeing a massive increase in impurity profiling. A drug substance or product will inevitably contain contaminants in trace amounts. According to pharmaceutical chemistry, impurities are undesirable...
2.
Ahmed S, Baba M, Wahedi U, Koppula J, Reddy M, Selvaraj D, et al.
Int J Biol Macromol
. 2024 Sep;
279(Pt 1):135487.
PMID: 39349339
The present study aims to prepare and evaluate solid lipid nanoparticles (SLNs) loaded with irinotecan (IRN) drug and daidzein (DZN) isoflavonoid and surface coated with ligand materials such as hyaluronic...
3.
Chinraj V, Reddy R, Selvaraj J, Sureshkumar R
Drug Res (Stuttg)
. 2024 Jan;
74(2):60-66.
PMID: 38286420
Parkinson's disease is the highest prevalent neurodegenerative disease in elderly individuals after Alzheimer's disease. The pathological identification for Parkinson's disease is loss of dopaminergic neurons in substantia nigra region of...
4.
Swaroop A, Negi P, Kar A, Mariappan E, Natarajan J, Namboori P K K, et al.
Cytokine Growth Factor Rev
. 2024 Jan;
76:48-76.
PMID: 38220583
This concise review navigates the intricate realm of Interleukin-6 (IL-6), an important member of the cytokine family. Beginning with an introduction to cytokines, this narrative review unfolds with the historical...
5.
Rymbai E, Sugumar D, Chakkittukandiyil A, Kothandan R, Selvaraj J, Selvaraj D
Life Sci
. 2023 Oct;
333:122144.
PMID: 37797687
Aim: The present study aims to identify selective estrogen receptor beta (ERβ) agonists and to evaluate the neuroprotective mechanism in Parkinson's disease (PD) models. Main Methods: In-silico studies were carried...
6.
Selvaraj N, Swaroop A, Mariappan E, Natarajan J, Thangavelu P, Selvaraj J
Anticancer Agents Med Chem
. 2023 Aug;
23(18):2056-2071.
PMID: 37608657
Background: Targeted therapies, specifically ErbB family tyrosine kinase inhibitors, have demonstrated potential for improving outcomes in patients with ErbB2-positive breast cancer. Despite their effectiveness, these therapies are associated with limitations,...
7.
Swaroop A, Namboori P, Esakkimuthukumar M, Praveen T, Nagarjuna P, Patnaik S, et al.
Comput Biol Med
. 2023 Jul;
163:107231.
PMID: 37421735
Interleukin-6 upregulation leads to various acute phase reactions such as local inflammation and systemic inflammation in many diseases like cancer, multiple sclerosis, rheumatoid arthritis, anemia, and Alzheimer's disease stimulating JAK/STAT3,...
8.
Repurposing of FDA Approved Drugs and Neuropep peptides as Anticancer Agents Against ErbB1 and ErbB2
Patnaik S, Swaroop A, Ravi Naik M, Selvaraj J, Chandrasekar M
Drug Res (Stuttg)
. 2023 Apr;
73(6):341-348.
PMID: 37068520
ErbB1 and ErbB2 are the most important biological targets in cancer drug discovery and development of dual inhibitors for the cancer therapy. FDA approved drugs and Neuropep peptides were used...
9.
B S N, Namboori P K K, Akey K, Sankaran S, Raman R, Natarajan J, et al.
J Biomol Struct Dyn
. 2023 Apr;
41(20):11017-11043.
PMID: 37054526
As breast cancer remains leading cause of cancer death globally, it is essential to develop an affordable breast cancer therapy in underdeveloped countries. Drug repurposing offers potential to address gaps...
10.
Kundu S, Swaroop A, Selvaraj J
Curr Top Med Chem
. 2023 Feb;
23(13):1155-1170.
PMID: 36733193
Metal-organic frameworks (MOFs) are porous, crystalline materials made up of organic ligands and metal ions/metal clusters linked by coordinative bonds. This large family is becoming increasingly popular for drug delivery...