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Juannan Chen

Explore the profile of Juannan Chen including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Liu Y, Li J, Zhang Y, Wang Y, Chen J, Bian Y, et al.
J Am Chem Soc . 2023 Jul; 145(29):16228-16237. PMID: 37460135
EGFR tyrosine kinase inhibitors have made remarkable success in targeted cancer therapy. However, therapeutic resistance inevitably occurred and EGFR-targeting therapy has been demonstrated to have limited efficacy or utility in...
2.
Zhang Y, Cheng Y, Chen J, Zheng K, You H
Nucleic Acids Res . 2021 Jun; 49(12):7179-7188. PMID: 34139007
A significant number of sequences in the human genome form noncanonical G-quadruplexes (G4s) with bulges or a guanine vacancy. Here, we systematically characterized the mechanical stability of parallel-stranded G4s with...