Juan Manuel Dominguez
Overview
Explore the profile of Juan Manuel Dominguez including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
389
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Recent Articles
11.
Ramos-Tomillero I, Perez-Chacon G, Somovilla-Crespo B, Sanchez-Madrid F, Cuevas C, Zapata J, et al.
ACS Omega
. 2020 Apr;
5(13):7424-7431.
PMID: 32280884
Bioconjugation is a key approach for the development of novel molecular entities with clinical applications. The biocompatibility and specificity of biomolecules such as peptides, proteins, and antibodies make these macromolecules...
12.
Dominguez J, Perez-Chacon G, Guillen M, Munoz-Alonso M, Somovilla-Crespo B, Cibrian D, et al.
J Hematol Oncol
. 2020 Apr;
13(1):32.
PMID: 32264921
Background: In the search for novel antibody-drug conjugates (ADCs) with therapeutic potential, it is imperative to identify novel targets to direct the antibody moiety. CD13 seems an attractive ADC target...
13.
Morgaz J, Ventura S, Munoz-Rascon P, Navarrete R, Perez J, Granados M, et al.
BMC Vet Res
. 2020 Feb;
16(1):54.
PMID: 32050965
Background: Intestinal ischemia-reperfusion (IR) is an important clinical occurrence seen in common diseases, such as gastric dilatation-volvulus in dogs or colic in horses. Limited data is available on the use...
14.
Ruiz-Lopez P, Dominguez J, Granados M
Vet Anaesth Analg
. 2020 Feb;
47(2):152-159.
PMID: 32007442
Objective: To review monitors currently available for the assessment of nociception-antinociception in veterinary medicine. Databases Used: PubMed, Web of Science and Google Scholar. The results were initially filtered manually based...
15.
Ruiz-Lopez P, Navarrete-Calvo R, Morgaz J, Dominguez J, Quiros-Carmona S, Munoz-Rascon P, et al.
Vet Anaesth Analg
. 2020 Feb;
47(2):183-190.
PMID: 32005619
Objective: To determine if acute opioid tolerance (AOT) or opioid-induced hyperalgesia (OIH) could develop and limit the remifentanil-induced reduction in the sevoflurane minimum alveolar concentration (MAC). The response to mechanical...
16.
Serrano-Rodriguez J, Mengual C, Quiros-Carmona S, Fernandez J, Dominguez J, Serrano-Caballero J, et al.
Vet Anaesth Analg
. 2019 Feb;
46(2):226-235.
PMID: 30713054
Objective: To assess the pharmacokinetics (PK) and conduct a clinical laboratory evaluation of acetaminophen in Beagle and Galgo Español (GE) dogs. Study Design: Prospective randomized experimental trial. Animals: A total...
17.
Fedeli E, Lancelot A, Dominguez J, Serrano J, Calvo P, Sierra T
Nanomaterials (Basel)
. 2019 Feb;
9(2).
PMID: 30699915
Two series of amphiphilic block copolymers with a hybrid linear-dendritic structure are presented. The compounds consisted of a hydrophilic poly (ethylene glycol) (PEG) block and a 2,2'-bis(hydroxymethyl)propionic acid (bis-MPA) dendron...
18.
Losada A, Munoz-Alonso M, Martinez-Diez M, Gago F, Dominguez J, Martinez-Leal J, et al.
Br J Cancer
. 2018 Nov;
119(11):1410-1420.
PMID: 30420615
Background: Through several not-fully-characterised moonlighting functions, translation elongation factor eEF1A2 is known to provide a fitness boost to cancer cells. Furthermore, eEF1A2 has been demonstrated to confer neoplastic characteristics on...
19.
Aviles P, Dominguez J, Guillen M, Munoz-Alonso M, Mateo C, Rodriguez-Acebes R, et al.
Mol Cancer Ther
. 2018 Feb;
17(4):786-794.
PMID: 29440297
In the search for novel payloads to design new antibody-drug conjugates (ADC), marine compounds represent an interesting opportunity given their unique chemical features. PM050489 is a marine compound that binds...
20.
Ramos-Tomillero I, Perez-Chacon G, Somovilla-Crespo B, Sanchez-Madrid F, Dominguez J, Cuevas C, et al.
Bioconjug Chem
. 2018 Feb;
29(4):1199-1208.
PMID: 29433317
The design and generation of complex multifunctional macromolecular structures by bioconjugation is a hot topic due to increasing interest in conjugates with therapeutic applications. In this regard, the development of...