Juan M Saavedra
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Explore the profile of Juan M Saavedra including associated specialties, affiliations and a list of published articles.
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91
Citations
2781
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Recent Articles
1.
Tache Y, Saavedra J
Cell Mol Neurobiol
. 2021 Oct;
42(2):311-313.
PMID: 34652580
This special Issue presents comprehensive and state-of-the-art advances in supporting the crucial role of the bidirectional interactions between the Brain-Gut Axis in health and diseases with an emphasis on the...
2.
Saavedra J
Physiology (Bethesda)
. 2021 Apr;
36(3):160-173.
PMID: 33904788
Beyond blood pressure control, angiotensin receptor blockers reduce common injury mechanisms, decreasing excessive inflammation and protecting endothelial and mitochondrial function, insulin sensitivity, the coagulation cascade, immune responses, cerebrovascular flow, and...
3.
Elkahloun A, Saavedra J
Biomed Pharmacother
. 2020 Sep;
131:110653.
PMID: 32942152
Background: Angiotensin receptor blockers (ARBs) reducing inflammation and protecting lung and brain function, could be of therapeutic efficacy in COVID-19 patients. Methods: Using GSEA, we compared our previous transcriptome analysis...
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Saavedra J
Pharmacol Res
. 2020 Apr;
156:104832.
PMID: 32304747
Angiotensin Receptor Blockers (ARBs) exhibit major pleiotropic protecting effects beyond their antihypertensive properties, including reduction of inflammation. ARBs directly protect the lung from the severe acute respiratory syndrome as a...
7.
Freyberg Z, Saavedra J
Cell Mol Neurobiol
. 2020 Feb;
40(2):189-190.
PMID: 32006222
Trace amines, including β-phenylethylamine, p-octopamine, p-tyramine, and tryptamine, are produced in high levels in invertebrates where they play major roles in homeostasis regulation in a manner similar to that of...
8.
Wang Y, Ruan W, Mi J, Xu J, Wang H, Cao Z, et al.
Brain Behav Immun
. 2020 Jan;
89:689-691.
PMID: 31917072
No abstract available.
9.
Elkahloun A, Saavedra J
Mol Neurobiol
. 2019 Dec;
57(3):1656-1673.
PMID: 31811565
Preclinical experiments and clinical trials demonstrated that angiotensin II AT receptor overactivity associates with aging and cellular senescence and that AT receptor blockers (ARBs) protect from age-related brain disorders. In...
10.
Ruan W, Li J, Xu Y, Wang Y, Zhao F, Yang X, et al.
Cell Mol Neurobiol
. 2019 Jan;
39(2):265-286.
PMID: 30607811
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long non-coding RNA contributing to protect the blood-brain barrier (BBB) after stroke. We searched for small molecules that may up-regulate MALAT1 and...