Juan Lopez-Gomez
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Explore the profile of Juan Lopez-Gomez including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
25
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Recent Articles
1.
Romero A, Cumplido-Laso G, Fernandez A, Moreno J, Canales J, Ferreira R, et al.
Amino Acids
. 2024 Dec;
57(1):1.
PMID: 39641818
Nucleotide-pyrophosphatases/phosphodiesterases (NPP/PDE) are membrane or secreted Zn-metallohydrolases of nucleoside-5´-monophosphate derivatives. They hydrolyze, for instance, ATP and 4-nitrophenyl-dTMP, and belong to the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family that contains seven members (ENPP1-ENPP7)....
2.
Gonzalez L, Robles N, Mota-Zamorano S, Valdivielso J, Gonzalez-Rodriguez L, Lopez-Gomez J, et al.
Sci Rep
. 2023 Jan;
13(1):1253.
PMID: 36690661
Nephrosclerosis patients are at an exceptionally high cardiovascular (CV) risk. We aimed to determine whether genetic variability represented by 38 tag-SNPs in genes of the cyclooxygenase pathway (PTGS1, PTGS2, PTGES,...
3.
Mota-Zamorano S, Gonzalez L, Robles N, Valdivielso J, Arevalo-Lorido J, Lopez-Gomez J, et al.
Ann Med
. 2022 Oct;
54(1):3039-3051.
PMID: 36314849
Background: Diabetic nephropathy (DN) has become the major cause of end-stage kidney disease and is associated to an extremely high cardiovascular (CV) risk. Methods: We screened 318 DN patients for...
4.
Gonzalez L, Robles N, Mota-Zamorano S, Arevalo-Lorido J, Valdivielso J, Lopez-Gomez J, et al.
Front Pharmacol
. 2022 May;
13:817020.
PMID: 35586043
Nephrosclerosis patients have a high cardiovascular (CV) risk that is very often of more concern than the renal disease itself. We aimed to determine whether variants in phospholipase-related genes, associated...
5.
Mota-Zamorano S, Gonzalez L, Robles N, Valdivielso J, Cancho B, Lopez-Gomez J, et al.
Genes (Basel)
. 2021 Dec;
12(12).
PMID: 34946941
Diabetic kidney disease (DKD) has been pointed out as a prominent cause of chronic and end-stage renal disease (ESRD). There is a genetic predisposition to DKD, although clinically relevant loci...
6.
Mota-Zamorano S, Robles N, Gonzalez L, Valdivielso J, Lopez-Gomez J, Cancho B, et al.
J Clin Med
. 2021 Sep;
10(17).
PMID: 34501433
Genes in the epoxygenase pathway of arachidonic acid metabolism leading to vasoactive eicosanoids, mainly 20-hydroxyeicosatetraenoic (20-HETE) and epoxyeicosatrienoic (EETs) acids, have been related to glucose-induced renal damage in preclinical reports....
7.
Gonzalez L, Robles N, Mota-Zamorano S, Valdivielso J, Lopez-Gomez J, Gervasini G
J Pers Med
. 2021 Aug;
11(8).
PMID: 34442416
Prostaglandin E2 (PGE2) is a major actor mediating renal injury. We aimed to determine genetic variability in the genes coding for its receptors () and study associations with nephrosclerosis risk...
8.
Mota-Zamorano S, Robles N, Lopez-Gomez J, Cancho B, Gonzalez L, Garcia-Pino G, et al.
EXCLI J
. 2021 May;
20:698-708.
PMID: 34040498
Preclinical studies indicate that arachidonic acid (AA)-derived eicosanoids contribute to hyperglycemia-induced kidney injury. We aimed to determine whether plasma and/or urinary levels of dihydroxyeicosatrienoic (DHETs) and 20-hydroxyeicosatetraenoic (20-HETE) acids are...
9.
Robles N, Lopez-Gomez J, Garcia-Pino G, Ferreira F, Alvarado R, Sanchez-Casado E, et al.
Clin Exp Med
. 2013 Jun;
14(3):315-20.
PMID: 23793995
α1-Microglobulin (α1M) is a low molecular weight protein and has been best characterized for detecting acute lesions of proximal tubules (Bonventre in Contrib Nephrol 156:213-219, 2007). This study has tried...