Juan Leal
Overview
Explore the profile of Juan Leal including associated specialties, affiliations and a list of published articles.
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7
Citations
380
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0
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Recent Articles
1.
Coxon A, Bready J, Min H, Kaufman S, Leal J, Yu D, et al.
Mol Cancer Ther
. 2010 Oct;
9(10):2641-51.
PMID: 20937592
AMG 386 is an investigational first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2. Although the therapeutic value...
2.
Payton M, Chung G, Yakowec P, Wong A, Powers D, Xiong L, et al.
Cancer Res
. 2006 Apr;
66(8):4299-308.
PMID: 16618755
In eukaryotic cells, cyclin-dependent kinase (CDK) complexes regulate the temporal progression of cells through the cell cycle. Deregulation in the cell cycle is an essential component in the evolution of...
3.
Diaz-Infante E, Mont L, Leal J, Garcia-Bolao I, Fernandez-Lozano I, Hernandez-Madrid A, et al.
Am J Cardiol
. 2005 Jun;
95(12):1436-40.
PMID: 15950566
About 30% of patients treated with cardiac resynchronization therapy (CRT) do not respond to treatment. The aim of this study was to identify clinical predictors of lack of improvement in...
4.
Haviv F, Bradley M, Kalvin D, Schneider A, Davidson D, Majest S, et al.
J Med Chem
. 2005 Apr;
48(8):2838-46.
PMID: 15828822
The heptapeptide 1, NAc-Gly-Val-DIle-Thr-Arg-Ile-ArgNHEt, a structurally modified fragment derived from the second type-1 repeat of thrombospondin-1 (TSP-1), is known to possess antiangiogenic activity. However, therapeutic utility could not be demonstrated...
5.
Oliner J, Min H, Leal J, Yu D, Rao S, You E, et al.
Cancer Cell
. 2004 Nov;
6(5):507-16.
PMID: 15542434
Angiopoietin-2 (Ang2) exhibits broad expression in the remodeling vasculature of human tumors but very limited expression in normal tissues, making it an attractive candidate target for antiangiogenic cancer therapy. To...
6.
Candinas R, Liu B, Leal J, Sperzel J, Frohlig G, Scharf C, et al.
Pacing Clin Electrophysiol
. 2002 Dec;
25(11):1540-5.
PMID: 12494609
The Autocapture algorithm enables automatic capture verification on a beat-by-beat basis by recognizing the evoked response signal following each pacemaker stimulus. The algorithm intends to increase patient safety while decreasing...
7.
Ahrazem O, Prieto A, Leal J, Jimenez-Barbero J, Bernabe M
Carbohydr Res
. 2002 Sep;
337(16):1503-6.
PMID: 12204613
The alkali-extractable water-soluble polysaccharide (F1SS) isolated from the cell wall of Apodus deciduus has been studied by methylation analysis and NMR spectroscopy, and its structure established as:where n approximately 130+/-10.