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Juan G Santiago

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Articles 121
Citations 1389
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Recent Articles
1.
Paul S, Alkhulaifi Y, Jaroslawski T, Hawks S, Santiago J
Environ Sci Technol . 2025 Feb; 59(7):3518-3526. PMID: 39957261
Flowable carbon slurries are actively studied and under development for charge transport in various electrochemical systems including flow capacitors, capacitive deionization cells, semi-solid flow batteries, and lithium extraction. However, much...
2.
Avaro A, Schwarzbach A, Jangra A, Bahga S, Santiago J
Anal Chim Acta . 2025 Jan; 1337():343553. PMID: 39800509
Background: Isotachophoresis (ITP) is a well-established electrokinetic method for separation and preconcentration of analytes. Several simulation tools for ITP have been published, but their use for experimental design is limited...
3.
Blanluet C, Kuo C, Bhattacharya A, Santiago J
Anal Chem . 2024 Apr; 96(19):7444-7451. PMID: 38684052
Next-generation sequencing offers highly multiplexed and accurate detection of nucleic acid sequences but at the expense of complex workflows and high input requirements. The ease of use of CRISPR-Cas12 assays...
4.
Ma K, Ramachandran A, Santiago J
Electrophoresis . 2024 Feb; 45(7-8):676-686. PMID: 38350722
Understanding electrokinetic transport in nanochannels and nanopores is essential for emerging biological and electrochemical applications. The viscoelectric effect is an important mechanism implicated in the increase of local viscosity due...
5.
Jangra A, Shriyam S, Santiago J, Bahga S
Electrophoresis . 2023 Dec; 45(7-8):599-608. PMID: 38059796
We present the development and demonstration of a neural network (NN) model for fast and accurate prediction of whether or not a chosen analyte is focused by an isotachophoresis (ITP)...
6.
Santiago J
QRB Discov . 2023 Aug; 3:e9. PMID: 37529278
The scientific and technological advent of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is one of the most exciting developments of the past decade, particularly in the field of gene...
7.
Avaro A, Santiago J
Lab Chip . 2023 Jan; 23(5):938-963. PMID: 36601854
Reviewed are nucleic acid detection assays that incorporate clustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostics and microfluidic devices and techniques. The review serves as a reference for researchers who...
8.
Blanluet C, Huyke D, Ramachandran A, Avaro A, Santiago J
Anal Chem . 2022 Oct; 94(43):15117-15123. PMID: 36251847
The specificity of CRISPR-Cas12 assays is attractive for the detection of single nucleotide polymorphisms (SNPs) implicated in, , cancer and SARS-CoV-2 variants. Such assays often employ endpoint measurements of SNP...
9.
Hoffman D, Bechtel H, Huyke D, Santiago J, DePonte D, Koralek J
Langmuir . 2022 Oct; 38(42):12822-12832. PMID: 36220141
Chemical reactions and biological processes are frequently governed by the structure and dynamics of the interface between two liquid phases, but these interfaces are often difficult to study due to...
10.
Avaro A, Santiago J
Angew Chem Int Ed Engl . 2022 Sep; 61(45):e202209527. PMID: 36117459
Michaelis-Menten kinetics is an essential model to rationalize enzyme reactions. The quantification of Michaelis-Menten parameters can be very challenging as it is sensitive to even small experimental errors. We here...