Juan E Abrahante
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Explore the profile of Juan E Abrahante including associated specialties, affiliations and a list of published articles.
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61
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1898
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Recent Articles
1.
Peixoto E, Pant K, Richard S, Abrahante J, Czaja W, Gradilone S
bioRxiv
. 2025 Feb;
PMID: 39975310
Primary cilia have been considered tumor-suppressing organelles in cholangiocarcinoma (CCA), though the mechanisms behind their protective role are not fully understood. This study investigates how the loss of primary cilia...
2.
Yamashita A, Garay B, Kim H, Bosnakovski D, Abrahante J, Azzag K, et al.
Stem Cell Reports
. 2025 Jan;
20(2):102396.
PMID: 39889709
Pax3-induced pluripotent stem cell-derived myogenic progenitors display an embryonic molecular signature but become postnatal upon transplantation. Because this correlates with upregulation of Notch signaling, here we probed whether NOTCH1 is...
3.
Fine J, Kosyakovsky J, Bowe T, Faltesek K, Stroebel B, Abrahante J, et al.
Front Neurosci
. 2025 Jan;
18:1528374.
PMID: 39872995
Introduction: Intranasal (IN) deferoxamine (DFO) has emerged over the past decade as a promising therapeutic in preclinical experiments across neurodegenerative and neurovascular diseases. As an antioxidant iron chelator, its mechanisms...
4.
Gorr S, Chen R, Abrahante J, Joyce P
PLoS One
. 2024 Oct;
19(10):e0312200.
PMID: 39446776
Porphyromonas gingivalis is a keystone pathogen for periodontal disease. The bacteria are black-pigmented and require heme for growth. P. gingivalis exhibit resistance to many antimicrobial peptides, which contributes to their...
5.
Yang L, Xia H, Smith K, Gilbertsen A, Jbeli A, Abrahante J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Oct;
327(6):L949-L963.
PMID: 39406384
The idiopathic pulmonary fibrosis (IPF) lung contains mesenchymal progenitor cells (MPCs) that display durable activation of oncogenic signaling and cell-autonomous fibrogenicity in vivo. Prior work identified a CD44/Brg1/PRMT5 nuclear regulatory...
6.
Mohamed M, Guo B, Wu B, Schladt D, Muthusamy A, Guan W, et al.
Pharmacogenomics J
. 2024 Aug;
24(5):29.
PMID: 39179559
African American (AA) kidney transplant recipients (KTRs) have poor outcomes, which may in-part be due to tacrolimus (TAC) sub-optimal immunosuppression. We previously determined the common genetic regulators of TAC pharmacokinetics...
7.
Waldron C, Kelly L, Stan N, Kawakami Y, Abrahante J, Magli A, et al.
Stem Cells Transl Med
. 2024 May;
13(7):678-692.
PMID: 38761090
Cardiomyocyte (CM) proliferation and maturation are highly linked processes, however, the extent to which these processes are controlled by a single signaling axis is unclear. Here, we show the previously...
8.
Johnson L, Abrahante J, McLoon L
Invest Ophthalmol Vis Sci
. 2024 Jan;
65(1):26.
PMID: 38206276
Purpose: Infantile nystagmus syndrome (INS) is a gaze-holding disorder characterized by conjugate, uncontrolled eye oscillations that can result in significant visual acuity loss. INS is often associated with albinism, but...
9.
Ye B, Bradshaw A, Abrahante J, Dragon J, Haussler T, Bell S, et al.
Circ Heart Fail
. 2023 Aug;
16(8):e010395.
PMID: 37582166
Background: Heart failure with preserved ejection fraction (HFpEF) is increasingly prevalent and has few treatments. The molecular mechanisms and resultant signaling pathways that underlie the development of HFpEF are poorly...
10.
Garay B, Givens S, Abreu P, Liu M, Yucel D, Baik J, et al.
Stem Cell Reports
. 2023 Jan;
18(1):411.
PMID: 36630905
No abstract available.