Juan Carlos Gallardo-Perez
Overview
Explore the profile of Juan Carlos Gallardo-Perez including associated specialties, affiliations and a list of published articles.
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44
Citations
792
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Recent Articles
1.
Trejo-Solis C, Escamilla-Ramirez A, Gomez-Manzo S, Castillo-Rodriguez R, Palomares-Alonso F, Castillo-Perez C, et al.
Biochimie
. 2025 Feb;
PMID: 39894336
The glioma hallmark includes reprogramming metabolism to support biosynthetic and bioenergetic demands, as well as to maintain their redox equilibrium. It has been suggested that the pentose phosphate pathway (PPP)...
2.
Trejo-Solis C, Serrano-Garcia N, Castillo-Rodriguez R, Robledo-Cadena D, Jimenez-Farfan D, Marin-Hernandez A, et al.
Rev Neurosci
. 2024 Jun;
35(7):813-838.
PMID: 38841811
Glioblastoma multiforme (GBM) exhibits genetic alterations that induce the deregulation of oncogenic pathways, thus promoting metabolic adaptation. The modulation of metabolic enzyme activities is necessary to generate nucleotides, amino acids,...
3.
Trejo-Solis C, Castillo-Rodriguez R, Serrano-Garcia N, Silva-Adaya D, Vargas-Cruz S, Chavez-Cortez E, et al.
Metabolites
. 2024 May;
14(5).
PMID: 38786726
The metabolic reprogramming that promotes tumorigenesis in glioblastoma is induced by dynamic alterations in the hypoxic tumor microenvironment, as well as in transcriptional and signaling networks, which result in changes...
4.
Gallardo-Perez J, Trejo-Solis M, Robledo-Cadena D, Lopez-Marure R, Agredano-Moreno L, Jimenez-Garcia L, et al.
Med Oncol
. 2023 Feb;
40(3):104.
PMID: 36821013
Glioblastoma (GBM) is the most frequent brain cancer and more lethal than other cancers. Characteristics of this cancer are its high drug resistance, high recurrence rate and invasiveness. Invasiveness in...
5.
Gallardo-Perez J, Adan-Ladron de Guevara A, Garcia-Amezcua M, Robledo-Cadena D, Pacheco-Velazquez S, Belmont-Diaz J, et al.
Curr Med Chem
. 2021 Oct;
29(15):2719-2735.
PMID: 34636290
Background: The major hurdles for successful cancer treatment are drug resistance and invasiveness developed by breast cancer stem cells (BCSC). Objective: As these two processes are highly energy-dependent, the identification...
6.
Moreno-Sanchez R, Gallardo-Perez J, Pacheco-Velazquez S, Robledo-Cadena D, Rodriguez-Enriquez S, Encalada R, et al.
Biochim Biophys Acta Gen Subj
. 2021 Oct;
1865(12):130021.
PMID: 34597724
Background: Most of the enzymes involved in the central carbon metabolism are acetylated in Lys residues. It has been claimed that this covalent modification represents a novel regulatory mechanism by...
7.
Rodriguez-Enriquez S, Robledo-Cadena D, Gallardo-Perez J, Pacheco-Velazquez S, Vazquez C, Saavedra E, et al.
Front Oncol
. 2021 Aug;
11:697408.
PMID: 34414111
Under dysbiosis, a gut metabolic disorder, short-chain carboxylic acids (SCCAs) are secreted to the lumen, affecting colorectal cancer (CRC) development. Butyrate and propionate act as CRC growth inhibitors, but they...
8.
Calleja L, Yoval-Sanchez B, Hernandez-Esquivel L, Gallardo-Perez J, Sosa-Garrocho M, Marin-Hernandez A, et al.
FEBS J
. 2021 Jan;
288(13):4064-4080.
PMID: 33400378
Under physiological conditions, cells produce low basal levels of reactive oxygen species (ROS); however, in pathologic conditions ROS production increases dramatically, generating high concentrations of toxic unsaturated aldehydes. Aldehyde dehydrogenases...
9.
Robledo-Cadena D, Gallardo-Perez J, Davila-Borja V, Pacheco-Velazquez S, Belmont-Diaz J, Ralph S, et al.
Pharmaceuticals (Basel)
. 2020 Dec;
13(12).
PMID: 33333716
This study shows that the non-steroidal anti-inflammatory drug (NSAID) celecoxib and its non-cyclooxygenase-2 (COX2) analogue dimethylcelecoxib (DMC) exert a potent inhibitory effect on the growth of human cervix HeLa multi-cellular...
10.
Duran-Maldonado M, Hernandez-Padilla L, Gallardo-Perez J, Diaz-Perez A, Martinez-Alcantar L, Reyes de la Cruz H, et al.
Front Oncol
. 2020 Aug;
10:1111.
PMID: 32793477
Melanoma is an aggressive cancer that utilizes multiple signaling pathways, including those that involve oncogenes, proto-oncogenes, and tumor suppressors. It has been suggested that melanoma formation requires cross-talk of the...