Juan Bacigalupo
Overview
Explore the profile of Juan Bacigalupo including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
314
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Recent Articles
1.
Delgado R, Wilson C, Caballero L, Melo F, Bacigalupo J
Neuroscience
. 2024 Jul;
555:23-31.
PMID: 39032804
Drosophila phototransduction in light-sensitive microvilli involves a metabotropic signaling cascade. Photoisomerized rhodopsin couples to G-protein, activating phospholipase C, which cleaves phosphatidylinositol bisphosphate (PIP2) into inositol trisphosphate, diacylglycerol (DAG) and a...
2.
Villar P, Vergara C, Bacigalupo J
FEBS J
. 2020 Nov;
288(12):3799-3812.
PMID: 33142020
Cells possess a variety of organelles with characteristic structure and subcellular localization intimately linked to their specific function. While most are intracellular and found in virtually all eukaryotic cells, there...
3.
Vera J, Pereira U, Reynaert B, Bacigalupo J, Sanhueza M
Neuroscience
. 2019 Dec;
426:13-32.
PMID: 31785354
Neurons from several brain regions resonate in the theta frequency range (4-12 Hz), displaying a higher voltage response to oscillatory currents at a preferred 'resonant' frequency (f). Subthreshold resonance could...
4.
Pina R, Ugarte G, Campos M, Inigo-Portugues A, Olivares E, Orio P, et al.
J Neurosci
. 2019 Sep;
39(41):8177-8192.
PMID: 31471469
The cornea is extensively innervated by trigeminal ganglion cold thermoreceptor neurons expressing TRPM8 (transient receptor potential cation channel subfamily M member 8). These neurons respond to cooling, hyperosmolarity and wetness...
5.
Acevedo C, Blanchard K, Bacigalupo J, Vergara C
FEBS Lett
. 2019 Feb;
593(6):601-610.
PMID: 30801684
Odor transduction in the cilia of olfactory sensory neurons involves several ATP-requiring enzymes. ATP is generated by glycolysis in the ciliary lumen, using glucose incorporated from surrounding mucus, and by...
6.
Delgado R, Delgado M, Bastin-Heline L, Glavic A, ODay P, Bacigalupo J
Neuroscience
. 2018 Nov;
396:66-72.
PMID: 30458219
Drosophila phototransduction occurs in light-sensitive microvilli arranged in a longitudinal structure of the photoreceptor, termed the rhabdomere. Rhodopsin (Rh), isomerized by light, couples to G-protein, which activates phospholipase C (PLC),...
7.
Mura C, Delgado R, Delgado M, Restrepo D, Bacigalupo J
BMC Neurosci
. 2017 Aug;
18(1):61.
PMID: 28800723
Background: CLCA is a family of metalloproteases that regulate Ca-activated Cl fluxes in epithelial tissues. In HEK293 cells, CLCA1 promotes membrane expression of an endogenous Anoctamin 1 (ANO1, also termed...
8.
Villar P, Delgado R, Vergara C, Reyes J, Bacigalupo J
J Neurosci
. 2017 May;
37(23):5736-5743.
PMID: 28500222
The mechanisms that power the physiological events occurring in cilia, flagella, and microvilli are of fundamental importance for the functions of these important and ubicuous organelles. The olfactory epithelium is...
9.
Delgado R, Mura C, Bacigalupo J
BMC Neurosci
. 2016 Apr;
17(1):17.
PMID: 27113933
Background: Odor transduction, occurring in the chemosensory cilia of vertebrate olfactory sensory neurons, is triggered by guanosine triphosphate-coupled odor receptors and mediated by a cyclic adenosine monophosphate (cAMP) signaling cascade,...
10.
Delgado R, Munoz Y, Pena-Cortes H, Giavalisco P, Bacigalupo J
J Neurosci
. 2014 May;
34(19):6679-86.
PMID: 24806693
Drosophila light-dependent channels, TRP and TRPL, reside in the light-sensitive microvilli of the photoreceptor's rhabdomere. Phospholipase C mediates TRP/TRPL opening, but the gating process remains unknown. Controversial evidence has suggested...