Juan-Ramon Larrubia
Overview
Explore the profile of Juan-Ramon Larrubia including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
173
Followers
0
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Recent Articles
1.
Pena-Asensio J, Calvo-Sanchez H, Miquel-Plaza J, Sanz-de-Villalobos E, Gonzalez-Praetorius A, Delgado-Fernandez A, et al.
Front Immunol
. 2024 Mar;
15:1352929.
PMID: 38545116
Background: HBe-antigen(Ag)-negative chronic hepatitis B virus (HBV) infection is characterized by little liver fibrosis progression and vigorous HBV-multispecific CD8 T-cell response. Aims: To assess whether HBsAg level could discriminate different...
2.
Pena-Asensio J, Calvo-Sanchez H, Miquel J, Sanz-de-Villalobos E, Gonzalez-Praetorius A, Torralba M, et al.
iScience
. 2023 Dec;
27(1):108666.
PMID: 38155778
A rebalance between energy supply and demand in HBV-specific-CD8 activated progenitor (AP) cells could restore the functionality of proliferative progeny (PP) in e-antigen(Ag)-negative chronic hepatitis B (CHBe(-)). We observed that...
3.
Pena-Asensio J, Calvo H, Miquel J, Sanz-de-Villalobos E, Gonzalez-Praetorius A, Torralba M, et al.
Aliment Pharmacol Ther
. 2022 Sep;
56(8):1312-1313.
PMID: 36168258
No abstract available.
4.
Pena-Asensio J, Calvo H, Miquel J, Sanz-de-Villalobos E, Gonzalez-Praetorius A, Torralba M, et al.
Aliment Pharmacol Ther
. 2022 Feb;
55(12):1545-1559.
PMID: 35224746
Background: Hepatitis B virus (HBV)-specific CD8 cell response restoration during nucleos(t)ide analogue (NUC) treatment could lead to off-treatment HBV control in e-antigen-negative chronic hepatitis B (CHBe(-)). Aim: To predict this...
5.
Pena-Asensio J, Calvo H, Torralba M, Miquel J, Sanz-de-Villalobos E, Larrubia J
Cancers (Basel)
. 2021 Apr;
13(8).
PMID: 33923463
Thirty to fifty percent of hepatocellular carcinomas (HCC) display an immune class genetic signature. In this type of tumor, HCC-specific CD8 T cells carry out a key role in HCC...
6.
Pena-Asensio J, Calvo H, Torralba M, Miquel J, Sanz-de-Villalobos E, Larrubia J
Cells
. 2021 Apr;
10(3).
PMID: 33802622
Hepatitis C virus (HCV)-specific CD8 T cell response is essential in natural HCV infection control, but it becomes exhausted during persistent infection. Nowadays, chronic HCV infection can be resolved by...
7.
Moreno-Cubero E, Subira D, Sanz-de-Villalobos E, Parra-Cid T, Madejon A, Miquel J, et al.
J Virol
. 2017 Nov;
92(2).
PMID: 29093082
Hepatitis C virus (HCV)-specific CD8 T cells suffer a progressive exhaustion during persistent infection (PI) with HCV. This process could involve the positive immune checkpoint 4-1BB/4-1BBL through the loss of...
8.
Moreno-Cubero E, Larrubia J
World J Gastroenterol
. 2016 Sep;
22(28):6469-83.
PMID: 27605882
Hepatocellular carcinoma (HCC), chronic hepatitis B (CHB) and chronic hepatitis C (CHC) are characterized by exhaustion of the specific CD8(+) T cell response. This process involves enhancement of negative co-stimulatory...
9.
Larrubia J, Moreno-Cubero E, Miquel J, Sanz-de-Villalobos E
World J Gastroenterol
. 2015 Apr;
21(12):3480-91.
PMID: 25834312
Hepatitis C virus (HCV)-specific cytotoxic T cell (CTL) response plays a major role in viral control during spontaneous infection resolution. These cells develop an exhausted and pro-apoptotic status during chronic...
10.
Larrubia J, Lokhande M, Moreno-Cubero E, Garcia-Garzon S, Miquel J, Parra-Cid T, et al.
Cell Immunol
. 2013 Nov;
286(1-2):31-8.
PMID: 24287274
Lower than 2-log viral-load (VL) decrease at week 12 (w12) of chronic hepatitis C (CHC) treatment with Peg-interferon/ribavirin has 100% negative predictive value (PV) of sustained virologic response (SVR), and...