Jozef Chorazyczewski
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Explore the profile of Jozef Chorazyczewski including associated specialties, affiliations and a list of published articles.
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9
Citations
269
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Recent Articles
1.
Ding Q, Chorazyczewski J, Gros R, Motulsky H, Limbird L, Feldman R
Pharmacol Res Perspect
. 2022 Sep;
10(5):e00995.
PMID: 36065843
Aldosterone exerts some of its effects not by binding to mineralocorticoid receptors, but rather by acting via G protein-coupled estrogen receptors (GPER). To determine if aldosterone binds directly to GPER,...
2.
Gros R, Hussain Y, Chorazyczewski J, Pickering J, Ding Q, Feldman R
Hypertension
. 2016 Oct;
68(5):1225-1235.
PMID: 27698063
Estrogens are important regulators of cardiovascular function. Some of estrogen's cardiovascular effects are mediated by a G-protein-coupled receptor mechanism, namely, G-protein-coupled estrogen receptor (GPER). Estradiol-mediated regulation of vascular cell programmed...
3.
Gros R, Ding Q, Liu B, Chorazyczewski J, Feldman R
Am J Physiol Cell Physiol
. 2013 Jan;
304(6):C532-40.
PMID: 23283935
The importance of the rapid vascular effects of aldosterone is increasingly appreciated. Through these rapid pathways, aldosterone has been shown to regulate vascular contractility, cell growth, and apoptosis. In our...
4.
Gros R, Ding Q, Davis M, Shaikh R, Liu B, Chorazyczewski J, et al.
Can J Physiol Pharmacol
. 2011 Aug;
89(9):655-63.
PMID: 21854125
It is increasingly appreciated that steroid hormones such as aldosterone and estradiol can mediate important cardiovascular effects. Many of these effects occur over a time course not consistent with the...
5.
Gros R, Ding Q, Sklar L, Prossnitz E, Arterburn J, Chorazyczewski J, et al.
Hypertension
. 2011 Jan;
57(3):442-51.
PMID: 21242460
It has been increasingly appreciated that steroids elicit acute vascular effects through rapid, so-called nongenomic signaling pathways. Though aldosterone, for example, has been demonstrated to mediate rapid vascular effects via...
6.
Estradiol-mediated ERK phosphorylation and apoptosis in vascular smooth muscle cells requires GPR 30
Ding Q, Gros R, Limbird L, Chorazyczewski J, Feldman R
Am J Physiol Cell Physiol
. 2009 Sep;
297(5):C1178-87.
PMID: 19741198
Recent studies suggest that the rapid and nongenomic effects of estradiol may be mediated through the G protein-coupled receptor dubbed GPR30 receptor. The present study examines the role of GPR30...
7.
Gros R, Ding Q, Chorazyczewski J, Pickering J, Limbird L, Feldman R
Circ Res
. 2006 Sep;
99(8):845-52.
PMID: 16973907
Compartmentation of cAMP signaling been demonstrated to be attributable to the structural association of protein kinase A (PKA) (via association with A-kinase anchoring proteins [AKAPs]) with phosphodiesterase and AKAP-dependent effector...
8.
Gros R, Ding Q, Chorazyczewski J, Andrews J, Pickering J, Hegele R, et al.
Mol Pharmacol
. 2005 Oct;
69(1):317-27.
PMID: 16223959
The effects of vasodilator hormones acting through receptors linked to adenylyl cyclase are impaired in the hypertensive state. This has been ascribed to impaired receptor-G protein coupling. However, these receptors...
9.
Ding Q, Gros R, Chorazyczewski J, Ferguson S, Feldman R
Mol Pharmacol
. 2004 Nov;
67(2):564-71.
PMID: 15547246
Oligomerization plays an important role in endoplasmic reticulum processing and membrane insertion (and ultimately in regulation of function) of a number of transmembrane spanning proteins. Furthermore, it is known that...