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Joy Olotu

Explore the profile of Joy Olotu including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 33
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Recent Articles
1.
Oladayo A, Gowans L, Awotoye W, Alade A, Busch T, Naicker T, et al.
Mol Genet Genomic Med . 2023 Jul; 11(10):e2237. PMID: 37496383
Introduction: The frequency and implications of secondary findings (SFs) from genomic testing data have been extensively researched. However, little is known about the frequency or reporting of SFs in Africans,...
2.
Naicker T, Alade A, Adeleke C, Mossey P, Awotoye W, Busch T, et al.
Mol Genet Genomic Med . 2023 Feb; 11(5):e2138. PMID: 36811272
Background: To date, there are over 320 variants identified in the IRF6 gene that cause Van der Woude syndrome or popliteal pterygium syndrome. We sequenced this gene in a South...
3.
Awotoye W, Mossey P, Hetmanski J, Gowans L, Eshete M, Adeyemo W, et al.
Cleft Palate Craniofac J . 2022 Nov; 61(4):697-705. PMID: 36384317
Novel or rare damaging mutations have been implicated in the developmental pathogenesis of nonsyndromic cleft lip with or without cleft palate (nsCL ± P). Thus, we investigated the human genome...
4.
Fashina A, Busch T, Young M, Adamson O, Awotoye W, Alade A, et al.
Front Oral Health . 2022 Aug; 3:915361. PMID: 35990505
Background: Several population-based case-control studies have reported concurrent presentation of cancer and congenital malformations. Many associations have been made between oral clefting and cancers, though some of these results are...
5.
Awotoye W, Mossey P, Hetmanski J, Gowans L, Eshete M, Adeyemo W, et al.
Sci Rep . 2022 Jul; 12(1):11743. PMID: 35817949
The majority (85%) of nonsyndromic cleft lip with or without cleft palate (nsCL/P) cases occur sporadically, suggesting a role for de novo mutations (DNMs) in the etiology of nsCL/P. To...
6.
Naicker T, Adeleke C, Alade A, Mossey P, Awotoye W, Busch T, et al.
Cleft Palate Craniofac J . 2021 Aug; 59(9):1125-1130. PMID: 34459660
Objective: The etiology of cleft palate (CP) is poorly understood compared with that of cleft lip with or without palate (CL ± P). Recently, variants in Grainyhead like transcription factor...
7.
Gowans L, Comnick C, Mossey P, Eshete M, Adeyemo W, Naicker T, et al.
Cleft Palate Craniofac J . 2021 Aug; 59(7):841-851. PMID: 34382870
Objective: Nonsyndromic cleft lip and/or cleft palate (NSCL/P) have multifactorial etiology where genetic factors, gene-environment interactions, stochastic factors, gene-gene interactions, and parent-of-origin effects (POEs) play cardinal roles. POEs arise when...
8.
Li M, Olotu J, Buxo-Martinez C, Mossey P, Anand D, Busch T, et al.
Oral Dis . 2021 Jun; 28(7):1921-1935. PMID: 34061439
Objectives: Cleft lip with/without cleft palate and cleft palate only is congenital birth defects where the upper lip and/or palate fail to fuse properly during embryonic facial development. Affecting ~1.2/1000 ...
9.
Olatosi O, Li M, Alade A, Oyapero A, Busch T, Pape J, et al.
BMC Oral Health . 2021 May; 21(1):274. PMID: 34016088
Background: Early childhood caries (ECC) is a rapidly progressing form of dental infection and a significant public health problem, especially among socially and economically disadvantaged populations. This study aimed to...
10.
Alade A, Buxo-Martinez C, Mossey P, Gowans L, Eshete M, Adeyemo W, et al.
Mol Genet Genomic Med . 2020 Jun; 8(8):e1355. PMID: 32558391
Background: The development of the face occurs during the early days of intrauterine life by the formation of facial processes from the first Pharyngeal arch. Derangement in these well-organized fusion...