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Joy Kirigo

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Citations 9
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Recent Articles
1.
Koshani R, Yeh S, Vom Steeg L, Pitcher M, Kirigo J, Leconey S, et al.
Biomaterials . 2025 Feb; 318:123141. PMID: 39965420
Vancomycin (VAN), a cationic glycopeptide antibiotic, represents a last-resort therapeutic remedy for life-threatening infections caused by multidrug resistant Gram-positive pathogens. However, biliary excretion of intravenously administered VAN in the gastrointestinal...
2.
Fernandez-Garcia L, Kirigo J, Huelgas-Mendez D, Benedik M, Tomas M, Garcia-Contreras R, et al.
Microb Biotechnol . 2024 Aug; 17(8):e14543. PMID: 39096350
Arguably, the greatest threat to bacteria is phages. It is often assumed that those bacteria that escape phage infection have mutated or utilized phage-defence systems; however, another possibility is that...
3.
Sanchez-Torres V, Kirigo J, Wood T
Curr Opin Microbiol . 2024 May; 79:102482. PMID: 38714140
Phage therapy holds much promise as an alternative to antibiotics for fighting infection. However, this approach is no panacea as recent results show that a small fraction of cells survives...
4.
Fernandez-Garcia L, Gao X, Kirigo J, Song S, Battisti M, Garcia-Contreras R, et al.
Microbiol Spectr . 2024 Jan; 12(2):e0347123. PMID: 38206055
Although toxin/antitoxin (TA) systems are ubiquitous, beyond phage inhibition and mobile element stabilization, their role in host metabolism is obscure. One of the best-characterized TA systems is MqsR/MqsA of ,...
5.
Fernandez-Garcia L, Song S, Kirigo J, Battisti M, Petersen M, Tomas M, et al.
Microbiol Spectr . 2023 Dec; 12(1):e0338823. PMID: 38054715
To date, there are no reports of phage infection-inducing persistence. Therefore, our results are important since we show for the first time that a phage-defense system, the MqsRAC toxin/antitoxin system,...