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Joung Han Yim

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Articles 101
Citations 814
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Recent Articles
1.
Kang P, Kim S, Park H, Han S, Kim I, Lee H, et al.
Plants (Basel) . 2025 Feb; 14(3). PMID: 39943009
The stable long-term preservation of plant cells is crucial for biopharmaceuticals and food security. Therefore, the long-term cryopreservation of plant cells using a cryoprotective agent (CPA) is a crucial area...
2.
Cho Y, Lee J, Kim J, Jeon Y, Han S, Cho H, et al.
Anim Cells Syst (Seoul) . 2025 Feb; 29(1):122-134. PMID: 39931645
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by cognitive decline, anxiety-like behavior, β-amyloid (Aβ) accumulation, and tau hyperphosphorylation. BACE1, the enzyme critical for Aβ production, has been a...
3.
Kim J, Cho Y, Lee J, Cho H, Han S, Lee Y, et al.
Biosci Trends . 2025 Jan; 19(1):102-115. PMID: 39864832
Alzheimer's disease (AD) is the most common type of dementia. Its incidence is rising rapidly as the global population ages, leading to a significant social and economic burden. AD involves...
4.
Liu Z, Yoon C, Cao T, Lee H, Kim I, Yim J, et al.
Molecules . 2025 Jan; 30(2. PMID: 39860162
Inflammation has always been considered a trigger or consequence of neurodegenerative diseases, and the inhibition of inflammation in the central nervous system can effectively protect nerve cells. Several studies have...
5.
Kim T, Hong J, Kim J, Kim K, Han S, Kim I, et al.
Molecules . 2024 Nov; 29(22). PMID: 39598614
Alzheimer's disease (AD) remains a significant public health challenge with limited effective treatment options. Ramalin, a compound derived from Antarctic lichens, has shown potential in the treatment of AD because...
6.
Liu Z, Yoon C, Lee H, Kim E, Yim J, Kim T, et al.
Biochem Pharmacol . 2024 Nov; 231:116654. PMID: 39581531
Ramalin, a strong antioxidant isolated from Antarctic lichens, has been shown to have potential therapeutic effects in the treatment of Alzheimer's disease. However, this compound is readily degraded in aqueous...
7.
Kim T, Cho Y, Kim J, Lee J, Hong J, Cho H, et al.
Molecules . 2024 Aug; 29(15). PMID: 39125105
Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by the accumulation of amyloid-beta plaques and hyperphosphorylated tau proteins, leading to cognitive decline and neuronal death. However, despite extensive research,...
8.
Kang P, Kim S, Park H, Kim I, Han S, Yim J
J Microbiol Biotechnol . 2024 Mar; 34(5):1135-1145. PMID: 38533592
When cells are exposed to freezing temperatures, high concentrations of cryoprotective agents (CPA) prevent ice crystal formation, thus enhancing cell survival. However, high concentrations of CPAs can also cause cell...
9.
Kwon H, Ann H, Park S, Kwon J, Park K, Ryu S, et al.
J Antibiot (Tokyo) . 2024 Jan; 77(4):257-263. PMID: 38243062
Using mass spectrometry (MS)-guided isolation methods, a new thiodiketopiperazine derivative (1) and exserohilone (2) were isolated from an EtOAc-extract of Setosphaeria rostrata culture medium. The chemical structure of the new...
10.
Kwon H, Jin B, Yoo S, Kim H, Hwang B, Guo Y, et al.
Bioorg Chem . 2024 Jan; 143:107070. PMID: 38190796
Three new fusidane-type nortriterpenoids, simplifusinolide A, 24-epi simplifusinolide A, and simplifusidic acid L (1-3), were isolated from the EtOAc extract of the Arctic marine-derived fungus Simplicillium lamellicola culture medium, together...