Joshua T Morgan
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Explore the profile of Joshua T Morgan including associated specialties, affiliations and a list of published articles.
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36
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728
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Recent Articles
1.
Hisey E, Wong S, Park S, Gamarra K, Adelman S, Knickelbein K, et al.
Ocul Surf
. 2024 Oct;
34:489-503.
PMID: 39414024
Purpose: There is an urgent need for animal models of meibomian gland dysfunction (MGD) and evaporative dry eye disease (EDED) to understand their pathophysiology and investigate novel therapeutics. This study...
2.
Kennedy S, Williams C, Tsaturian E, Morgan J
Curr Issues Mol Biol
. 2024 Sep;
46(9):9867-9880.
PMID: 39329939
Mitochondrial damage occurs in human trabecular meshwork (HTM) cells as a result of normal aging and in open angle glaucoma. Using an HTM cell model, we quantified mitochondrial function and...
3.
Rolsma J, Darch W, Higgins N, Morgan J
Sci Rep
. 2024 May;
14(1):11834.
PMID: 38783150
Human adipose-derived stem cell (ASC) grafts have emerged as a powerful tool in regenerative medicine. However, ASC therapeutic potential is hindered by stressors throughout their use. Here we demonstrate the...
4.
Cassano J, Leonard B, Martins B, Vapniarsky N, Morgan J, Dow S, et al.
Front Vet Sci
. 2024 Jan;
10:1293199.
PMID: 38162475
Introduction: Equine recurrent uveitis (ERU), an immune mediated disease characterized by repeated episodes of intra-ocular inflammation, affects 25% of horses in the USA and is the most common cause of...
5.
Bagdasarian I, Tonmoy T, Park B, Morgan J
PLoS One
. 2023 Nov;
18(11):e0293609.
PMID: 37910543
3D cell culture models have gained popularity in recent years as an alternative to animal and 2D cell culture models for pharmaceutical testing and disease modeling. Polydimethylsiloxane (PDMS) is a...
6.
Sanchez M, Tonmoy T, Park B, Morgan J
Biomolecules
. 2022 Dec;
12(12).
PMID: 36551256
Photoaging is an important extrinsic aging factor leading to altered skin morphology and reduced function. Prior work has revealed a connection between photoaging and loss of subcutaneous fat. Currently, primary...
7.
Sanchez M, Bagdasarian I, Darch W, Morgan J
Aging (Albany NY)
. 2022 Nov;
14(22):9338-9383.
PMID: 36435511
Aging remains a primary risk factor for a host of diseases, including leading causes of death. Aging and associated diseases are inherently multifactorial, with numerous contributing factors and phenotypes at...
8.
Kim S, Chaurasiya S, Sivanandam V, Kang S, Park A, Lu J, et al.
Mol Ther Oncolytics
. 2022 Mar;
24:864-872.
PMID: 35317522
Pancreatic cancer resistance to immunotherapies is partly due to deficits in tumor-infiltrating immune cells and stromal density. Combination therapies that modify stroma and recruit immune cells are needed. Vitamin D...
9.
Sanchez M, Orneles D, Park B, Morgan J
Biotechniques
. 2022 Mar;
72(5):194-200.
PMID: 35289681
Human skin equivalents (HSEs) are models of human skin. They are used to study skin development, diseases, wound healing and toxicity. The gold standard of analysis is histological sectioning, which...
10.
Sanchez M, Morgan J
J Vis Exp
. 2021 Mar;
(168).
PMID: 33645584
Human skin equivalents (HSEs) are tissue engineered constructs that model epidermal and dermal components of human skin. These models have been used to study skin development, wound healing, and grafting...