Joshua R Gershlak
Overview
Explore the profile of Joshua R Gershlak including associated specialties, affiliations and a list of published articles.
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10
Citations
353
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Recent Articles
1.
Chrobak M, Hansen K, Gershlak J, Vratsanos M, Kanellias M, Gaudette G, et al.
ACS Biomater Sci Eng
. 2021 Jan;
3(7):1394-1403.
PMID: 33429697
The ability to modulate the mechanical properties, and cell alignment within a cardiac patch without hindering cell functionality may have significant impact on developing therapies for treating myocardial infarctions. We...
2.
Gershlak J, Ott H
Transplantation
. 2020 Jun;
104(7):1310-1311.
PMID: 32569000
No abstract available.
3.
Moser P, Gerli M, Diercks G, Evangelista-Leite D, Charest J, Gershlak J, et al.
Tissue Eng Part A
. 2019 Oct;
26(9-10):543-555.
PMID: 31663421
Current reconstruction methods of the laryngotracheal segment fail to replace the complex functions of the human larynx. Bioengineering approaches to reconstruction have been limited by the complex tissue compartmentation of...
4.
Adamski M, Fontana G, Gershlak J, Gaudette G, Le H, Murphy W
J Vis Exp
. 2018 Jun;
(135).
PMID: 29912197
The autologous, synthetic, and animal-derived grafts currently used as scaffolds for tissue replacement have limitations due to low availability, poor biocompatibility, and cost. Plant tissues have favorable characteristics that make...
5.
Hansen K, Favreau J, Gershlak J, Laflamme M, Albrecht D, Gaudette G
Tissue Eng Part C Methods
. 2017 Jun;
23(8):445-454.
PMID: 28562232
Differentiation of human pluripotent stem cells into cardiomyocytes (hPS-CMs) holds promise for myocardial regeneration therapies, drug discovery, and models of cardiac disease. Potential cardiotoxicities may affect hPS-CM mechanical contraction independent...
6.
Jank B, Goverman J, Guyette J, Charest J, Randolph M, Gaudette G, et al.
Tissue Eng Part A
. 2017 Mar;
23(13-14):696-707.
PMID: 28323545
Full-thickness skin loss is a challenging problem due to limited reconstructive options, demanding 75 million surgical procedures annually in the United States. Autologous skin grafting is the gold standard treatment,...
7.
Gershlak J, Hernandez S, Fontana G, Perreault L, Hansen K, Larson S, et al.
Biomaterials
. 2017 Feb;
125:13-22.
PMID: 28222326
Despite significant advances in the fabrication of bioengineered scaffolds for tissue engineering, delivery of nutrients in complex engineered human tissues remains a challenge. By taking advantage of the similarities in...
8.
Guyette J, Charest J, Mills R, Jank B, Moser P, Gilpin S, et al.
Circ Res
. 2015 Oct;
118(1):56-72.
PMID: 26503464
Rationale: More than 25 million individuals have heart failure worldwide, with ≈4000 patients currently awaiting heart transplantation in the United States. Donor organ shortage and allograft rejection remain major limitations...
9.
Gershlak J, Black 3rd L
Exp Cell Res
. 2014 Sep;
330(2):311-324.
PMID: 25220424
We have previously reported a unique response of traction force generation for cells grown on mature cardiac ECM, where traction force was constant over a range of stiffnesses. In this...
10.
Gershlak J, Resnikoff J, Sullivan K, Williams C, Wang R, Black 3rd L
Biochem Biophys Res Commun
. 2013 Sep;
439(2):161-6.
PMID: 23994333
In this study we present a novel method for studying cellular traction force generation and mechanotransduction in the context of cardiac development. Rat hearts from three distinct stage of development...