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Joshua E Donovan

Explore the profile of Joshua E Donovan including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 29
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Recent Articles
1.
Hejenkowska E, Mitash N, Donovan J, Chandra A, Bertrand C, de Santi C, et al.
J Innate Immun . 2023 Aug; 15(1):629-646. PMID: 37579743
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for COVID-19, utilizes receptor binding domain (RBD) of spike glycoprotein to interact with angiotensin (Ang)-converting enzyme 2 (ACE2). Altering ACE2 levels...
2.
Mitash N, Donovan J, Swiatecka-Urban A
J Vis Exp . 2020 Sep; (161). PMID: 32894261
Micro(mi)RNAs are short, non-coding RNAs that mediate the RNA interference (RNAi) by post-transcriptional mechanisms. Specific miRNAs are recruited to the cytoplasmic RNA induced silencing complex (RISC). Argonaute2 (Ago2), an essential...
3.
Mitash N, Donovan J, Swiatecka-Urban A
Int J Mol Sci . 2020 Jun; 21(11). PMID: 32481719
Mucociliary clearance, mediated by a coordinated function of cilia bathing in the airway surface liquid (ASL) on the surface of airway epithelium, protects the host from inhaled pathogens and is...
4.
Mitash N, Mu F, Donovan J, Myerburg M, Ranganathan S, M Greene C, et al.
Int J Mol Sci . 2019 Oct; 20(19). PMID: 31590401
<p>Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (<italic>CFTR</italic>) gene lead to cystic fibrosis (CF). The most common mutation F508del inhibits folding and processing of CFTR protein. FDA-approved correctors rescue...