Joseph Schlessinger
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Explore the profile of Joseph Schlessinger including associated specialties, affiliations and a list of published articles.
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123
Citations
10655
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Recent Articles
1.
Schlessinger J, Bennet R, Coakwell J, Smith S, Kao E
Sci Rep
. 2025 Jan;
15(1):1110.
PMID: 39774624
Reporting by major media outlets influences news coverage by other outlets, resulting in an outsized impact on public opinion. Understanding this inter-outlet influence, known as intermedia agenda setting, is important...
2.
Chen X, Ojalill M, Jean C, Tancioni I, Jiang S, Boyer A, et al.
bioRxiv
. 2024 Nov;
PMID: 39574770
Impact Statement: PYK2-null combined with endothelial cell-specific FAK transgenic mouse models show that loss of FAK activity limits tumor spread and that genetic or chemical degradation preventing combined FAK-PYK2 expression...
3.
Edman N, Phal A, Redler R, Schlichthaerle T, Srivatsan S, Ehnes D, et al.
Cell
. 2024 Jun;
187(14):3726-3740.e43.
PMID: 38861993
Many growth factors and cytokines signal by binding to the extracellular domains of their receptors and driving association and transphosphorylation of the receptor intracellular tyrosine kinase domains, initiating downstream signaling...
4.
Kamen L, Schlessinger J, Lowell C
J Immunol
. 2024 May;
212(10):1604.
PMID: 38709995
No abstract available.
5.
Bellone S, Jeong K, Halle M, Krakstad C, McNamara B, Greenman M, et al.
Proc Natl Acad Sci U S A
. 2024 Apr;
121(17):e2321898121.
PMID: 38625939
High-grade neuroendocrine cervical cancers (NETc) are exceedingly rare, highly aggressive tumors. We analyzed 64 NETc tumor samples by whole-exome sequencing (WES). Human papillomavirus DNA was detected in 65.6% (42/64) of...
6.
Edman N, Redler R, Phal A, Schlichthaerle T, Srivatsan S, Etemadi A, et al.
bioRxiv
. 2023 Mar;
PMID: 36993355
Growth factors and cytokines signal by binding to the extracellular domains of their receptors and drive association and transphosphorylation of the receptor intracellular tyrosine kinase domains, initiating downstream signaling cascades....
7.
McNamara B, Harold J, Manavella D, Bellone S, Mutlu L, Hartwich T, et al.
Gynecol Oncol
. 2023 Mar;
172:65-71.
PMID: 36958197
Introduction: Uterine leiomyosarcomas (uLMS) are rare, highly aggressive tumors. Up to 30% of uLMS may harbor gain of function (GOF) in the MAP2K4 gene, important for tumor cell proliferation, differentiation...
8.
Krimmer S, Bertoletti N, Suzuki Y, Katic L, Mohanty J, Shu S, et al.
Proc Natl Acad Sci U S A
. 2023 Mar;
120(13):e2300054120.
PMID: 36943885
The receptor tyrosine kinase KIT and its ligand stem cell factor (SCF) are required for the development of hematopoietic stem cells, germ cells, and other cells. A variety of human...
9.
An S, Mohanty J, Tome F, Suzuki Y, Lax I, Schlessinger J
Proc Natl Acad Sci U S A
. 2023 Feb;
120(7):e2219128120.
PMID: 36745784
While important insights were gained about how FGF21 and other endocrine fibroblast growth factors (FGFs) bind to Klotho proteins, the exact mechanism of Klotho/FGF receptor assembly that drives receptor dimerization...
10.
Krimmer S, Schlessinger J
Proc Natl Acad Sci U S A
. 2022 Dec;
119(50):e2218237119.
PMID: 36475945
No abstract available.