Joseph S Pagano
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Explore the profile of Joseph S Pagano including associated specialties, affiliations and a list of published articles.
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69
Citations
2560
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Recent Articles
1.
Wahl A, Yao W, Liao B, Chateau M, Richardson C, Ling L, et al.
Nat Biotechnol
. 2023 Aug;
42(6):905-915.
PMID: 37563299
Germ-free (GF) mice, which are depleted of their resident microbiota, are the gold standard for exploring the role of the microbiome in health and disease; however, they are of limited...
2.
Whitehurst C, Rizk M, Teklezghi A, Spagnuolo R, Pagano J, Wahl A
Front Virol
. 2022 May;
2.
PMID: 35611388
In most individuals, EBV maintains a life-long asymptomatic latent infection. However, EBV can induce the formation of B cell lymphomas in immune suppressed individuals including people living with HIV (PLWH)....
3.
Atkins S, Motaib S, Wiser L, Hopcraft S, Hardy P, Shackelford J, et al.
Antiviral Res
. 2019 Nov;
173:104649.
PMID: 31711927
Herpesviral deubiquitinating enzymes (DUBs) were discovered in 2005, are highly conserved across the family, and are proving to be increasingly important players in herpesviral infection. EBV's DUB, BPLF1, is known...
4.
Kobayashi E, Hwang D, Bheda-Malge A, Whitehurst C, Kabanov A, Kondo S, et al.
Int J Mol Sci
. 2019 Aug;
20(15).
PMID: 31370144
Normally ubiquitin C-terminal hydrolase L1 (UCH-L1) is expressed in the central nervous and reproductive systems of adults, but its de novo expression has been detected in many human cancers. There...
5.
Salahuddin S, Fath E, Biel N, Ray A, Moss C, Patel A, et al.
Sci Rep
. 2019 Jan;
9(1):208.
PMID: 30659232
Epstein-Barr Virus latent membrane protein-1 (LMP1) interacts with the SUMO-conjugating enzyme Ubc9, which induces protein sumoylation and may contribute to LMP1-mediated oncogenesis. After analyzing human lymphoma tissues and EBV-positive cell...
6.
Salahuddin S, Khan J, Azhar J, Whitehurst C, Qadri I, Shackelford J, et al.
Asian Pac J Cancer Prev
. 2018 Nov;
19(11):3153-3159.
PMID: 30486603
The Epstein-Barr virus (EBV) is a herpesvirus infecting more than 90% of the human population. The tropism of
EBV for B lymphocytes is evidenced in its association with many lymphoproliferative...
7.
Pagano J, Whitehurst C, Andrei G
Cancers (Basel)
. 2018 Jun;
10(6).
PMID: 29899236
Epstein⁻Barr virus (EBV) infects up to 95% of the adult human population, with primary infection typically occurring during childhood and usually asymptomatic. However, EBV can cause infectious mononucleosis in approximately...
8.
Dyson O, Pagano J, Whitehurst C
J Virol
. 2017 Jul;
91(19).
PMID: 28724765
Epstein-Barr virus (EBV) infection and lytic replication are known to induce a cellular DNA damage response. We previously showed that the virally encoded BPLF1 protein interacts with and regulates several...
9.
Kondo S, Endo K, Wakisaka N, Aga M, Kano M, Seishima N, et al.
Pathol Int
. 2017 Jul;
67(9):461-466.
PMID: 28712115
Interferon regulatory factor 7 (IRF7) has oncogenic properties in several malignancies such as Epstein-Barr virus (EBV)-associated lymphoma. However, there is no evidence whether IRF7 is associated with the oncogenesis of...
10.
Elgui De Oliveira D, Muller-Coan B, Pagano J
Trends Microbiol
. 2016 Apr;
24(8):649-664.
PMID: 27068530
Cancer progression begins when malignant cells colonize adjacent sites, and it is characterized by increasing tumor heterogeneity, invasion and dissemination of cancer cells. Clinically, progression is the most relevant stage...