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Joseph Robert McCorkle

Explore the profile of Joseph Robert McCorkle including associated specialties, affiliations and a list of published articles. Areas
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Citations 152
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Recent Articles
1.
Myint Z, Kolesar J, McCorkle J, Wu J, Ellis C, Otto D, et al.
Med Sci Monit . 2022 Oct; 28:e938091. PMID: 36229939
BACKGROUND Prostate cancer growth is primarily driven by testosterone and 5a-dihydrotestosterone. Abiraterone is an irreversible inhibitor of CYP17, and CYP17 inhibition is a required step in testosterone biosynthesis. Previous studies...
2.
Diouf B, Crews K, Lew G, Pei D, Cheng C, Bao J, et al.
JAMA . 2015 Feb; 313(8):815-23. PMID: 25710658
Importance: With cure rates of childhood acute lymphoblastic leukemia (ALL) exceeding 85%, there is a need to mitigate treatment toxicities that can compromise quality of life, including peripheral neuropathy from...
3.
Stocco G, Yang W, Crews K, Thierfelder W, Decorti G, Londero M, et al.
Hum Mol Genet . 2012 Aug; 21(21):4793-804. PMID: 22846425
Treatment-related toxicity can be life-threatening and is the primary cause of interruption or discontinuation of chemotherapy for acute lymphoblastic leukemia (ALL), leading to an increased risk of relapse. Mercaptopurine is...