Joseph R Ghilardi
Overview
Explore the profile of Joseph R Ghilardi including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
2012
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Recent Articles
11.
Honore P, Chandran P, Hernandez G, Gauvin D, Mikusa J, Zhong C, et al.
Pain
. 2009 Jan;
142(1-2):27-35.
PMID: 19135797
Transient receptor potential vanilloid type 1 (TRPV1) is a ligand-gated ion channel that functions as an integrator of multiple pain stimuli including heat, acid, capsaicin and a variety of putative...
12.
Halvorson K, Sevcik M, Ghilardi J, Sullivan L, Koewler N, Bauss F, et al.
J Pain Symptom Manage
. 2008 Apr;
36(3):289-303.
PMID: 18411018
Over half of all chronic cancer pain arises from metastases to bone and bone cancer pain is one of the most difficult of all persistent pain states to fully control....
13.
Jimenez-Andrade J, Herrera M, Ghilardi J, Vardanyan M, Melemedjian O, Mantyh P
Mol Pain
. 2008 Mar;
4:10.
PMID: 18353190
Although a variety of industrial chemicals, as well as several chemotherapeutic agents used to treat cancer or HIV, preferentially induce a peripheral sensory neuropathy what remains unclear is why these...
14.
A fracture pain model in the rat: adaptation of a closed femur fracture model to study skeletal pain
Freeman K, Koewler N, Jimenez-Andrade J, Buus R, Herrera M, Martin C, et al.
Anesthesiology
. 2008 Feb;
108(3):473-83.
PMID: 18292685
Background: Because of the relative lack of understanding of the mechanisms that drive skeletal pain, the purpose of this study was to adapt a previously validated closed femur fracture model...
15.
Martin C, Jimenez-Andrade J, Ghilardi J, Mantyh P
Neurosci Lett
. 2007 Oct;
427(3):148-52.
PMID: 17950532
Although bone fracture frequently results in significant pain and can lead to increased morbidity and mortality, it is still not clearly understood how sensory neurons are organized to detect fracture...
16.
Peters C, Jimenez-Andrade J, Kuskowski M, Ghilardi J, Mantyh P
Brain Res
. 2007 Aug;
1168:46-59.
PMID: 17698044
Paclitaxel (Taxol) is a frontline antineoplastic agent used to treat a variety of solid tumors including breast, ovarian, or lung cancer. The major dose limiting side effect of paclitaxel is...
17.
Jimenez-Andrade J, Martin C, Koewler N, Freeman K, Sullivan L, Halvorson K, et al.
Pain
. 2007 Aug;
133(1-3):183-96.
PMID: 17693023
Current therapies to treat skeletal fracture pain are extremely limited. Some non-steroidal anti-inflammatory drugs have been shown to inhibit bone healing and opiates induce cognitive dysfunction and respiratory depression which...
18.
Koewler N, Freeman K, Buus R, Herrera M, Jimenez-Andrade J, Ghilardi J, et al.
J Bone Miner Res
. 2007 Jul;
22(11):1732-42.
PMID: 17638576
Unlabelled: A closed femur fracture pain model was developed in the C57BL/6J mouse. One day after fracture, a monoclonal antibody raised against nerve growth factor (anti-NGF) was delivered intraperitoneally and...
19.
Peters C, Jimenez-Andrade J, Jonas B, Sevcik M, Koewler N, Ghilardi J, et al.
Exp Neurol
. 2006 Sep;
203(1):42-54.
PMID: 17005179
Paclitaxel-induced peripheral neuropathy (PN) can be a significant problem for patients receiving chemotherapeutic regimens for the treatment of breast, ovarian, and lung cancer as PN can influence the quality of...
20.
Sevcik M, Jonas B, Lindsay T, Halvorson K, Ghilardi J, Kuskowski M, et al.
Gastroenterology
. 2006 Sep;
131(3):900-10.
PMID: 16952558
Background & Aims: The endogenous opioid system is involved in modulating the experience of pain, the response to stress, and the action of analgesic therapies. Recent human imaging studies have...