Joseph P Stains
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Explore the profile of Joseph P Stains including associated specialties, affiliations and a list of published articles.
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Articles
72
Citations
1939
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Recent Articles
1.
Buck H, Torre O, Leser J, Gould N, Ward C, Stains J
Biochem Biophys Res Commun
. 2024 Jul;
727:150315.
PMID: 38950493
In response to mechanical loading of bone, osteocytes produce nitric oxide (NO•) and decrease sclerostin protein expression, leading to an increase in bone mass. However, it is unclear whether NO•...
2.
Kumar A, Brown R, Roufaeil D, Gupta A, Lipford E, Muthusamy D, et al.
Adv Sci (Weinh)
. 2024 Jan;
11(11):e2306683.
PMID: 38183347
3D bioprinting holds great promise for meeting the increasing need for transplantable tissues and organs. However, slow printing, interlayer mixing, and the extended exposure of cells to non-physiological conditions in...
3.
Leser J, Torre O, Gould N, Guo Q, Buck H, Kodama J, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(47):e2304492120.
PMID: 37976259
Bone regulates its mass and quality in response to diverse mechanical, hormonal, and local signals. The bone anabolic or catabolic responses to these signals are often received by osteocytes, which...
4.
Kim S, Seward A, Garcia-Diaz J, Alekos N, Gould N, Aja S, et al.
iScience
. 2023 Aug;
26(7):106999.
PMID: 37534168
The nuclear receptor peroxisome proliferator activated receptor-γ (PPARγ) is a key contributor to metabolic function via its adipogenic and insulin-sensitizing functions, but it has negative effects on skeletal homeostasis. Here,...
5.
Leser J, Harriot A, Buck H, Ward C, Stains J
Front Rehabil Sci
. 2022 Aug;
2.
PMID: 36004321
The decline in the mass and function of bone and muscle is an inevitable consequence of healthy aging with early onset and accelerated decline in those with chronic disease. Termed...
6.
Bernier M, Enamorado I, Gomez-Cabrera M, Calvo-Rubio M, Gonzalez-Reyes J, Price N, et al.
NPJ Aging
. 2022 Aug;
8(1):8.
PMID: 35927269
Skeletal muscle adapts to different exercise training modalities with age; however, the impact of both variables at the systemic and tissue levels is not fully understood. Here, adult and old...
7.
Gould N, Leser J, Torre O, Khairallah R, Ward C, Stains J
Bio Protoc
. 2022 Jan;
11(23):e4251.
PMID: 35005095
Bone is a dynamic tissue that adapts to changes in its mechanical environment. Mechanical stimuli pressurize interstitial fluid in the lacunar-canalicular system within the bone matrix, causing fluid shear stress...
8.
Aljohani H, Senbanjo L, Al Qranei M, Stains J, Chellaiah M
Front Physiol
. 2021 Oct;
12:708905.
PMID: 34671266
Methylsulfonylmethane (MSM) is a naturally occurring anti-inflammatory compound that effectively treats multiple degenerative diseases such as osteoarthritis and acute pancreatitis. Our previous studies have demonstrated the ability of MSM to...
9.
Geist Hauserman J, Stavusis J, Joca H, Robinett J, Hanft L, Vandermeulen J, et al.
JCI Insight
. 2021 Aug;
6(19).
PMID: 34437302
Myosin binding protein-C slow (sMyBP-C) comprises a subfamily of cytoskeletal proteins encoded by MYBPC1 that is expressed in skeletal muscles where it contributes to myosin thick filament stabilization and actomyosin...
10.
Gould N, Torre O, Leser J, Stains J
Bone
. 2021 Apr;
149:115971.
PMID: 33892173
Bone is a mechano-responsive tissue that adapts to changes in its mechanical environment. Increases in strain lead to increased bone mass acquisition, whereas decreases in strain lead to a loss...