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Joseph Nasser

Explore the profile of Joseph Nasser including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 1387
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Recent Articles
11.
Marshall J, Doughty B, Subramanian V, Guckelberger P, Wang Q, Chen L, et al.
Proc Natl Acad Sci U S A . 2020 Dec; 117(52):33404-33413. PMID: 33376219
Single-cell quantification of RNAs is important for understanding cellular heterogeneity and gene regulation, yet current approaches suffer from low sensitivity for individual transcripts, limiting their utility for many applications. Here...
12.
Bick A, Weinstock J, Nandakumar S, Fulco C, Bao E, Zekavat S, et al.
Nature . 2020 Oct; 586(7831):763-768. PMID: 33057201
Age is the dominant risk factor for most chronic human diseases, but the mechanisms through which ageing confers this risk are largely unknown. The age-related acquisition of somatic mutations that...
13.
Fulco C, Nasser J, Jones T, Munson G, Bergman D, Subramanian V, et al.
Nat Genet . 2019 Dec; 51(12):1664-1669. PMID: 31784727
Enhancer elements in the human genome control how genes are expressed in specific cell types and harbor thousands of genetic variants that influence risk for common diseases. Yet, we still...
14.
Hormozdiari F, van de Geijn B, Nasser J, Weissbrod O, Gazal S, Ju C, et al.
Nat Commun . 2019 Sep; 10(1):4054. PMID: 31492842
Transposable elements (TE) comprise roughly half of the human genome. Though initially derided as junk DNA, they have been widely hypothesized to contribute to the evolution of gene regulation. However,...
15.
Reshef Y, Finucane H, Kelley D, Gusev A, Kotliar D, Ulirsch J, et al.
Nat Genet . 2018 Sep; 50(10):1483-1493. PMID: 30177862
Biological interpretation of genome-wide association study data frequently involves assessing whether SNPs linked to a biological process, for example, binding of a transcription factor, show unsigned enrichment for disease signal....
16.
Bartlett C, Taylor S, Trites J, Nasser J, Hart R
J Otolaryngol Head Neck Surg . 2009 May; 38(2):197-207. PMID: 19442369
Objectives: The T stage of oral cavity and oropharyngeal squamous cell cancer lesions has a significant impact on patient treatment and overall outcome. Determining the presence and size of palpable...