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Joseph M Mrus

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Articles 32
Citations 547
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Recent Articles
1.
Rizzardini G, Overton E, Orkin C, Swindells S, Arasteh K, Gorgolas Hernandez-Mora M, et al.
J Acquir Immune Defic Syndr . 2020 Nov; 85(4):498-506. PMID: 33136751
Background: Long-acting (LA) injectable regimens are a potential therapeutic option in people living with HIV-1. Setting: ATLAS (NCT02951052) and FLAIR (NCT02938520) were 2 randomized, open-label, multicenter, multinational phase 3 studies....
2.
Mills A, Brunet L, Fusco J, Wohlfeiler M, Garris C, Oglesby A, et al.
Infect Dis Ther . 2019 Nov; 9(1):41-52. PMID: 31701370
Introduction: Dolutegravir (DTG), Elvitegravir (EVG), Raltegravir (RAL) and Darunavir (DRV) are commonly prescribed core agents for antiretroviral therapy (ART), and a need exists to compare their clinical effectiveness, as defined...
3.
Hill A, Cho M, Mrus J
AIDS Rev . 2011 Mar; 13(1):41-8. PMID: 21412388
The aim of antiretroviral treatment is long-term suppression of plasma HIV RNA<50 copies/ml. The DUET, BENCHMRK, and MOTIVATE trials evaluated the efficacy of etravirine, raltegravir, and maraviroc, respectively, versus placebo,...
4.
Fullerton D, Smets E, De La Rosa G, Mrus J
Expert Rev Pharmacoecon Outcomes Res . 2011 Mar; 11(1):27-39. PMID: 21351854
Darunavir boosted with ritonavir (DRV/r) in combination with other antiretrovirals (ARVs) was initially approved in 2006 for the treatment of HIV infection in ARV treatment-experienced adults and has subsequently been...
5.
Willig J, Aban I, Nevin C, Ye J, Raper J, McKinnel J, et al.
AIDS Res Hum Retroviruses . 2010 Oct; 26(12):1279-85. PMID: 20961276
Several new antiretroviral (ARV) agents for treatment experienced HIV-infected patients have been approved since June 2006, including darunavir (DRV) and raltegravir (RAL). While efficacious in clinical trials, the effectiveness, durability,...
6.
Fullerton D, Watson M, Anderson D, Witek J, Martin S, Mrus J
Expert Rev Pharmacoecon Outcomes Res . 2010 Oct; 10(5):485-95. PMID: 20950062
HIV infection, particularly multidrug-resistant HIV, continues to be a major societal and economic challenge worldwide. Etravirine, a new (US FDA approved in 2008) non-nucleoside reverse transcriptase inhibitor, has been shown...
7.
Tsevat J, Leonard A, Szaflarski M, Sherman S, Cotton S, Mrus J, et al.
AIDS Patient Care STDS . 2009 Oct; 23(11):931-7. PMID: 19821724
The objective of this study was to assess in patients with HIV perceptions of life pre-HIV versus post-HIV diagnosis and examine whether such perceptions change over time. We conducted interviews...
8.
Nader C, Tsevat J, Justice A, Mrus J, Levin F, Kozal M, et al.
AIDS Patient Care STDS . 2009 Jun; 23(7):521-9. PMID: 19538046
Common symptoms associated with HIV disease and its management are often underrecognized and undertreated. A clinical decision support tool for symptom management was developed within the Veterans Health Administration electronic...
9.
McKinnell J, Lin H, Nevin C, Willig J, McFarland G, Genz M, et al.
AIDS . 2009 Jun; 23(12):1539-46. PMID: 19487910
Objective: To evaluate 24-week virologic effectiveness of novel antiretroviral regimens for treatment of three-class experienced adult patients in a clinical practice setting following the US Food and Drug Administration approval...
10.
Butt A, Tsevat J, Ahmad J, Shakil A, Mrus J
Am J Med Sci . 2007 May; 333(5):271-5. PMID: 17505167
Background: Previous studies of patients with hepatitis C virus (HCV) infection looking at the effect of human immunodeficiency virus (HIV) co-infection on biochemical parameters and HCV RNA level have shown...