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Joseph M DiRienzo

Explore the profile of Joseph M DiRienzo including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 280
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Recent Articles
1.
Kawamoto D, Ando-Suguimoto E, Bueno-Silva B, DiRienzo J, Mayer M
Front Cell Infect Microbiol . 2016 Apr; 6:33. PMID: 27064424
The dysbiotic microbiota associated with aggressive periodontitis includes Aggregatibacter actinomycetemcomitans, the only oral species known to produce a cytolethal distending toxin (AaCDT). Give that CDT alters the cytokine profile in...
2.
DiRienzo J
Toxins (Basel) . 2014 Nov; 6(11):3098-116. PMID: 25365527
The cytolethal distending toxin (Cdt) is a heterotrimeric holotoxin produced by a diverse group of Gram-negative pathogenic bacteria. The Cdts expressed by the members of this group comprise a subclass...
3.
DiRienzo J
Cells . 2014 May; 3(2):476-99. PMID: 24861975
The Gram-negative bacterium Aggregatibacter actinomycetemcomitans is part of the HACEK group that causes infective endocarditis, a constituent of the oral flora that promotes some forms of periodontal disease and a...
4.
Ando-Suguimoto E, da Silva M, Kawamoto D, Chen C, DiRienzo J, Mayer M
Cytokine . 2014 Feb; 66(1):46-53. PMID: 24548424
Aggregatibacter actinomycetemcomitans is an important periodontal pathogen that can participate in periodontitis and other non-oral infections. The cytolethal distending toxin (Cdt) is among the virulence factors produced by this bacterium....
5.
Damek-Poprawa M, Jang J, Volgina A, Korostoff J, DiRienzo J
Infect Immun . 2012 May; 80(8):2761-70. PMID: 22645284
The cytolethal distending toxin (Cdt), produced by some clinically important Gram-negative bacterial species, is related to the family of AB-type toxins. Three heterologous proteins (CdtA, CdtB, and CdtC) and a...
6.
DiRienzo J, Cao L, Volgina A, Bandelac G, Korostoff J
FEMS Microbiol Lett . 2008 Dec; 291(2):222-31. PMID: 19087203
Chimeras composed of the cdtB gene of a novel bacterial genotoxin and the human type I DNAse I gene were constructed and their products characterized relative to the biochemical and...
7.
Cao L, Bandelac G, Volgina A, Korostoff J, DiRienzo J
Infect Immun . 2008 Apr; 76(7):2812-21. PMID: 18426882
The periodontal pathogen Aggregatibacter actinomycetemcomitans produces a cytolethal distending toxin (Cdt) that inhibits the proliferation of oral epithelial cells. Structural models suggest that the CdtA and CdtC subunits of the...
8.
Doungudomdacha S, Volgina A, DiRienzo J
J Med Microbiol . 2007 Oct; 56(Pt 11):1519-1527. PMID: 17965355
The authors have previously shown that the periodontal pathogen Aggregatibacter (formerly Actinobacillus) actinomycetemcomitans Y4 contains an operon for a genotoxin known as the cytolethal distending toxin (Cdt). The cdt locus...
9.
Bowe W, Filip J, DiRienzo J, Volgina A, Margolis D
J Drugs Dermatol . 2006 Oct; 5(9):868-70. PMID: 17039652
We report the in vitro inhibition of Propionibacterium acnes (P. acnes) by a bacteriocin-like inhibitory substance (BLIS-like substance) produced by Streptococcus salivarius (S. salivarius). Bacteriocins are proteinaceous substances produced by...
10.
Cao L, Volgina A, Korostoff J, DiRienzo J
Infect Immun . 2006 Aug; 74(9):4990-5002. PMID: 16926390
The cytolethal distending toxin (Cdt) of Actinobacillus actinomycetemcomitans is an atypical A-B-type toxin consisting of a heterotrimer composed of the cdtA, cdtB, and cdtC gene products. The CdtA and CdtC...