Joseph J Bellucci
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Explore the profile of Joseph J Bellucci including associated specialties, affiliations and a list of published articles.
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7
Citations
125
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Recent Articles
1.
Manzari M, Anderson G, Lin K, Soderquist R, Cakir M, Zhang M, et al.
Sci Adv
. 2019 Sep;
5(9):eaaw9162.
PMID: 31517048
Extrinsic pathway agonists have failed repeatedly in the clinic for three core reasons: Inefficient ligand-induced receptor multimerization, poor pharmacokinetic properties, and tumor intrinsic resistance. Here, we address these factors by...
2.
Yousefpour P, Ahn L, Tewksbury J, Saha S, Costa S, Bellucci J, et al.
Small
. 2019 Feb;
15(12):e1804452.
PMID: 30756483
Short circulation time and off-target toxicity are the main challenges faced by small-molecule chemotherapeutics. To overcome these shortcomings, an albumin-binding peptide conjugate of chemotherapeutics is developed that binds specifically to...
3.
Bhattacharyya J, Bellucci J, Weitzhandler I, McDaniel J, Spasojevic I, Li X, et al.
Nat Commun
. 2015 Aug;
6:7939.
PMID: 26239362
Packaging clinically relevant hydrophobic drugs into a self-assembled nanoparticle can improve their aqueous solubility, plasma half-life, tumour-specific uptake and therapeutic potential. To this end, here we conjugated paclitaxel (PTX) to...
4.
Bellucci J, Bhattacharyya J, Chilkoti A
Angew Chem Int Ed Engl
. 2014 Nov;
54(2):441-5.
PMID: 25363491
We provide the first demonstration that isopeptide ligation, a noncanonical activity of the enzyme sortase A, can be used to modify recombinant proteins. This reaction was used in vitro to...
5.
Bellucci J, Amiram M, Bhattacharyya J, McCafferty D, Chilkoti A
Angew Chem Int Ed Engl
. 2013 Feb;
52(13):3703-8.
PMID: 23424160
No abstract available.
6.
Hamaker K, Johnson D, Bellucci J, Apgar K, Soslow S, Gercke J, et al.
Biotechnol Prog
. 2011 Apr;
27(3):657-67.
PMID: 21485036
Large-scale fermentation of Pichia pastoris requires a large volume of methanol feed during the induction phase. However, a large volume of methanol feed is difficult to use in the processing...
7.
Bellucci J, Hamaker K
Biotechnol Prog
. 2011 Apr;
27(2):368-76.
PMID: 21485030
Several methods are available for determining the volumetric oxygen transfer coefficient in bioreactors, though their application in industrial bioprocess has been limited. To be practically useful, mass transfer measurements made...