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Joseph Irudayaraj

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Articles 183
Citations 2585
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Recent Articles
1.
Han X, Ju L, Sands M, Zhao Y, Irudayaraj J
ACS Pharmacol Transl Sci . 2025 Feb; 8(2):602-612. PMID: 39974628
The rapid and organized healing of the cornea, while maintaining optical clarity, is essential for patient health and quality of life following corneal injuries. Oxygen plays a critical role in...
2.
Qiu M, Man C, Zhao Q, Yang X, Zhang Y, Zhang W, et al.
Adv Colloid Interface Sci . 2025 Jan; 338:103404. PMID: 39884113
Nanozyme, a class of emerging enzyme mimics, is the nanomaterials with enzyme-mimicking activity, which has obtained significant and widespread applications in various fields. However, they still face many challenges in...
3.
Sands M, Zhang X, Irudayaraj J
Sci Total Environ . 2024 Oct; 955:177019. PMID: 39447891
Exposure to emerging energy-based environmental contaminants such as lithium bis(trifluoromethanesulfonyl)imide (LiTFSI, trade name HQ-115), poses a significant threat to human health, yet its impact on kidney function and epigenetic regulation...
4.
Gnanasambandam B, Prince J, Limaye S, Moran E, Lee B, Huynh J, et al.
Ther Adv Ophthalmol . 2024 Oct; 16:25158414241280187. PMID: 39376745
Retinal hypoxia stands as a pivotal yet often underappreciated factor in the etiology and progression of many retinal disorders such as glaucoma, hypertensive retinopathy, diabetic retinopathy, retinal vein occlusions, and...
5.
Jeong Y, Hsieh P, Phal Y, Bhargava R, Irudayaraj J
Anal Chem . 2024 Jun; 96(28):11247-11254. PMID: 38941069
Evaluating the dynamic interaction of microorganisms and mammalian cells is challenging due to the lack of suitable platforms for examining interspecies interactions in biologically relevant coculture conditions. In this work,...
6.
Ren W, Sands M, Han X, Tsipursky M, Irudayaraj J
ACS Omega . 2024 Jun; 9(22):24095-24104. PMID: 38854553
Herein, we propose a Carbopol hydrogel-based oxygen nanodelivery "nanohyperbaric" system as a wound dressing material for an enhanced wound healing process. Oxygen nanobubbles (ONBs) were used to supply oxygen, and...
7.
Jeong Y, Han X, Vyas K, Irudayaraj J
ACS Appl Mater Interfaces . 2024 May; 16(22):28093-28103. PMID: 38775441
Bacteria-assisted chemotherapeutics have been highlighted as an alternative or supplementary approach to treating cancer. However, dynamic cancer-microbe studies at the level have remained a challenge to show the impact and...
8.
Boyd R, Shokry D, Fazal Z, Rennels B, Freemantle S, La Frano M, et al.
Toxics . 2024 Apr; 12(4). PMID: 38668455
The potential effects of poly- and perfluoroalkyl substances (PFAS) are a recently emergent human and environmental health concern. There is a consistent link between PFAS exposure and cancer, but the...
9.
Han X, Saengow C, Ju L, Ren W, Ewoldt R, Irudayaraj J
Nat Commun . 2024 Apr; 15(1):3435. PMID: 38653959
Wound healing is an obvious clinical concern that can be hindered by inadequate angiogenesis, inflammation, and chronic hypoxia. While exosomes derived from adipose tissue-derived stem cells have shown promise in...
10.
Sands M, Zhang X, Jensen T, La Frano M, Lin M, Irudayaraj J
Sci Total Environ . 2024 Apr; 927:172357. PMID: 38614344
Per- and Polyfluoroalkyl substances (PFAS) have been widely used in various industries, including pesticide production, electroplating, packaging, paper making, and the manufacturing of water-resistant clothes. This study investigates the levels...