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Joseph I Shapiro

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Articles 185
Citations 4246
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Recent Articles
1.
Lakhani H, Zehra M, Pillai S, Shapiro J, Sodhi K
J Clin Med Sci . 2024 Sep; 8(2). PMID: 39238841
Angiotensin II (AngII), a component of the Renin-Angiotensin-Aldosterone System (RAAS), has been implicated in the dysregulation of adipose tissue function. Inhibition of AngII has been shown to improve adipose tissue...
2.
Chen V, Zhang J, Chang J, Beg M, Vick L, Wang D, et al.
Front Cardiovasc Med . 2024 Aug; 11:1436865. PMID: 39156133
Visceral white adipose tissues (WAT) regulate systemic lipid metabolism and inflammation. Dysfunctional WAT drive chronic inflammation and facilitate atherosclerosis. Adipose tissue-associated macrophages (ATM) are the predominant immune cells in WAT,...
3.
Sodhi K, Maxwell K, Yan Y, Liu J, Chaudhry M, Xie Z, et al.
J Clin Med Sci . 2024 Jan; 7(4). PMID: 38283397
Obesity is a growing public health crisis across the world and has been recognized as an underlying risk factor for metabolic syndrome. Growing evidence demonstrates the critical role of oxidative...
4.
Sodhi K, Pratt R, Wang X, Lakhani H, Pillai S, Zehra M, et al.
iScience . 2023 Dec; 26(12):108438. PMID: 38047077
[This corrects the article DOI: 10.1016/j.isci.2021.103262.].
5.
Sodhi K, Wang X, Chaudhary M, Lakhani H, Zehra M, Nawab A, et al.
Cell Mol Biol (Noisy-le-grand) . 2023 Aug; 69(5):197-206. PMID: 37571879
Oxidative stress has been shown to cause an alteration of intracellular signaling in adipocytes that may lead to various comorbidities of obesity and cardiovascular complications. Evidence suggests that dysregulation of...
6.
Pillai S, Pereira D, Zhang J, Huang W, Beg M, Knaack D, et al.
Front Cardiovasc Med . 2023 May; 10:1046495. PMID: 37180782
Introduction: Adipose tissue constantly secretes adipokines and extracellular vesicles including exosomes to crosstalk with distinct tissues and organs for whole-body homeostasis. However, dysfunctional adipose tissue under chronic inflammatory conditions such...
7.
Mukherji S, Brambilla L, Stuart K, Mayes I, Kutz L, Chen Y, et al.
FASEB J . 2023 Mar; 37(4):e22835. PMID: 36856735
Through its classic ATP-dependent ion-pumping function, basolateral Na/K-ATPase (NKA) generates the Na gradient that drives apical Na reabsorption in the renal proximal tubule (RPT), primarily through the Na /H exchanger...
8.
Wagner B, Malhotra D, Schmidt D, Raj D, Khitan Z, Shapiro J, et al.
Kidney360 . 2023 Feb; 4(4):e555-e561. PMID: 36758190
Hypertonic saline infusion is used to correct hyponatremia with severe symptoms. The selection of the volume of infused hypertonic saline ( VInf ) should address prevention of overcorrection or undercorrection....
9.
Zhang J, Chang J, Beg M, Huang W, Zhao Y, Dai W, et al.
iScience . 2022 Sep; 25(9):104963. PMID: 36072548
Na/K-ATPase (NKA), besides its ion transporter function, is a signal transducer by regulating Src family kinases (SFK). The signaling NKA contributes to oxidized LDL-induced macrophage foam cell formation and interacts...
10.
Cooper C, Shapiro J, Dworkin L
J Am Heart Assoc . 2022 Aug; 11(17):e025900. PMID: 35975744
No abstract available.