Joseph H Chewning
Overview
Explore the profile of Joseph H Chewning including associated specialties, affiliations and a list of published articles.
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20
Citations
515
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Recent Articles
11.
Robillard D, Kutny M, Chewning J, Arbuckle J
J Pediatr Adolesc Gynecol
. 2017 Jan;
30(3):431-434.
PMID: 28062243
Background: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Relapse of ALL occurs in 15%-20% of patients, with 2%-6% occurring exclusively in extramedullary sites. Relapse of ALL in...
12.
Venstrom J, Dupont B, Hsu K, Pittari G, Gooley T, Chewning J, et al.
N Engl J Med
. 2014 Nov;
371(21):2042.
PMID: 25409391
No abstract available.
13.
Chewning J, Weaver C
J Immunol
. 2014 Nov;
193(10):4769-77.
PMID: 25381358
Th17 cells have emerged as important mediators of host defense and homeostasis at barrier sites, particularly the intestines, where the greatest number and diversity of the microbiota reside. A critical...
14.
Pittari G, Liu X, Selvakumar A, Zhao Z, Merino E, Huse M, et al.
J Immunol
. 2013 Apr;
190(9):4650-60.
PMID: 23554313
NK cells are regulated by inhibiting and activating cell surface receptors. Most inhibitory receptors recognize MHC class I Ags and protect healthy cells from NK cell-mediated autoaggression. However, certain activating...
15.
Chewning J, Zhang W, Randolph D, Swindle C, Schoeb T, Weaver C
Biol Blood Marrow Transplant
. 2013 Mar;
19(6):876-87.
PMID: 23523972
Bone marrow graft failure and poor graft function are frequent complications after hematopoietic stem cell transplantation and result in significant morbidity and mortality. Both conditions are associated with graft-versus-host disease...
16.
Venstrom J, Pittari G, Gooley T, Chewning J, Spellman S, Haagenson M, et al.
N Engl J Med
. 2012 Aug;
367(9):805-16.
PMID: 22931314
Background: Of the cancers treated with allogeneic hematopoietic stem-cell transplantation (HSCT), acute myeloid leukemia (AML) is most sensitive to natural killer (NK)-cell reactivity. The activating killer-cell immunoglobulin-like receptor (KIR) 2DS1...
17.
18.
Chewning J, Dugger K, Chaudhuri T, Zinn K, Weaver C
BMC Immunol
. 2009 Aug;
10:44.
PMID: 19650922
Background: Rapid clonal expansion of T cells occurs in response to antigenic challenges. The kinetics of the T cell response has previously been described using tissue-based studies performed at defined...
19.
Chewning J, Castro-Malaspina H, Jakubowski A, Kernan N, Papadopoulos E, Small T, et al.
Biol Blood Marrow Transplant
. 2007 Oct;
13(11):1313-23.
PMID: 17950918
Graft failure is associated with a high mortality rate. To date, regimens invoked for second transplants have resulted in inconsistent engraftment with high transplant-related mortality (TRM). We here report 16...
20.
Chewning J, Gudme C, Hsu K, Selvakumar A, Dupont B
J Immunol
. 2007 Jul;
179(2):854-68.
PMID: 17617576
The inhibitory 2DL1 and activating 2DS1 killer Ig-like receptors (KIR) both have shared ligand specificity for codon sequences in the C2 group HLA-Cw Ags. In this study, we have investigated...