Joseph G Stowell
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Explore the profile of Joseph G Stowell including associated specialties, affiliations and a list of published articles.
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11
Citations
60
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Recent Articles
1.
Li H, Wen H, Stowell J, Morris K, Byrn S
J Pharm Sci
. 2010 Jul;
99(9):3839-48.
PMID: 20589945
In reality, no crystal is perfect. Crystals bear defects both in the bulk and on the surface. The purpose of this project is to study the correlation between crystal defect...
2.
Chen X, Stowell J, Morris K, Byrn S
J Pharm Biomed Anal
. 2009 Nov;
51(4):866-74.
PMID: 19906502
The purpose of this study is to investigate solid-state acid-base reactions between polymorphs of flufenamic acid (FFA) and magnesium oxide (MgO) using X-ray powder diffraction (XRPD). Polymorphs of FFA were...
3.
Li H, Stowell J, He X, Morris K, Byrn S
J Pharm Sci
. 2007 Apr;
96(5):1079-89.
PMID: 17455331
Solid-solid transformation of 5-methyl-2-[(4-methyl-2-nitrophenyl)amino]-3-thiophenecarbonitrile from the dark-red to the red form was investigated. By controlled crystallization, the dark-red form was prepared and the crystals were sieved into fractions: coarse (>250...
4.
Snorek S, Bauer J, Chidambaram N, Doub W, Duffy E, Etzler F, et al.
J Pharm Sci
. 2007 Jan;
96(6):1451-67.
PMID: 17238204
This document provides information for the Pharmaceutical Industry and the Federal Drug Administration (FDA) regarding the selection of suitable particle-size analysis techniques, development and validation of particle-size methods, and the...
5.
Qiu Z, Stowell J, Cao W, Morris K, Byrn S, Carvajal M
J Pharm Sci
. 2005 Oct;
94(11):2568-80.
PMID: 16200560
The effects of milling and compression on the solid-state Maillard reaction between metoclopramide hydrochloride and lactose were investigated. Anhydrous metoclopramide hydrochloride was milled for various times, and then mixed with...
6.
Qiu Z, Stowell J, Morris K, Byrn S, Pinal R
Int J Pharm
. 2005 Aug;
303(1-2):20-30.
PMID: 16126356
The purpose of this work is to study the apparent solid-state kinetics of the Maillard reaction of the colyophilized metoclopramide hydrochloride (MCP) and lactose system and to elucidate some of...
7.
Chen X, Griesser U, Te R, Pfeiffer R, Morris K, Stowell J, et al.
J Pharm Biomed Anal
. 2005 Jun;
38(4):670-7.
PMID: 15967295
Indomethacin was used as a model compound to investigate acid-base reactions of solid materials, a common type of drug-excipient interaction. In a typical experiment, 500 mg of pure alpha-form indomethacin...
8.
Davis T, Peck G, Stowell J, Morris K, Byrn S
Pharm Res
. 2004 Jun;
21(5):860-6.
PMID: 15180346
Purpose: The purpose of this work was to monitor polymorphic transformations of glycine during the drying phase of a wet granulation and model the polymorphic conversions using a time-based reconciliation...
9.
Davis T, Morris K, Huang H, Peck G, Stowell J, Eisenhauer B, et al.
Pharm Res
. 2003 Dec;
20(11):1851-7.
PMID: 14661932
Purpose: Polymorphic transformations during the wet granulation of a metastable polymorph of flufenamic acid were monitored in situ using online X-ray powder diffraction. The resulting data were used in testing...
10.
Chen X, Morris K, Griesser U, Byrn S, Stowell J
J Am Chem Soc
. 2002 Dec;
124(50):15012-9.
PMID: 12475345
The present study deals with the acid-base reaction of three solid-state forms of the nonsteroidal antiinflammatory drug indomethacin with ammonia gas. X-ray powder diffraction, optical microscopy, gravimetry, and spectroscopic methods...