Joseph D Orkin
Overview
Explore the profile of Joseph D Orkin including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
324
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Recent Articles
1.
Fong-Zazueta R, Krueger J, Alba D, Aymerich X, Beck R, Cappellini E, et al.
Genome Biol Evol
. 2025 Jan;
17(2).
PMID: 39834226
Ancient tooth enamel, and to some extent dentin and bone, contain characteristic peptides that persist for long periods of time. In particular, peptides from the enamel proteome (enamelome) have been...
2.
Orkin J, Kuderna L, Hermosilla-Albala N, Fontsere C, Aylward M, Janiak M, et al.
Nat Ecol Evol
. 2024 Dec;
9(1):42-56.
PMID: 39730835
Ecological variation and anthropogenic landscape modification have had key roles in the diversification and extinction of mammals in Madagascar. Lemurs represent a radiation with more than 100 species, constituting roughly...
3.
Campos F, Wikberg E, Orkin J, Park Y, Snyder-Mackler N, Hernandez S, et al.
Philos Trans R Soc Lond B Biol Sci
. 2024 Oct;
379(1916):20230482.
PMID: 39463253
Studying biological ageing in animal models can circumvent some of the confounds exhibited by studies of human ageing. Ageing research in non-human primates has provided invaluable insights into human lifespan...
4.
Orkin J, He K, Hu N, Guan Z, Huang B, Yang C, et al.
Am J Primatol
. 2024 Jul;
87(1):e23662.
PMID: 39041384
Despite decades of field study, very little is known about the molecular ecology of gibbons, particularly as it relates to their ability to disperse across degraded and fragmentary landscapes. The...
5.
Webb S, Orkin J, Williamson R, Melin A
Anim Microbiome
. 2023 Dec;
5(1):63.
PMID: 38102711
Background: Energy demands associated with pregnancy and lactation are significant forces in mammalian evolution. To mitigate increased energy costs associated with reproduction, female mammals have evolved behavioural and physiological responses....
6.
Kuderna L, Ulirsch J, Rashid S, Ameen M, Sundaram L, Hickey G, et al.
Nature
. 2023 Nov;
625(7996):735-742.
PMID: 38030727
Noncoding DNA is central to our understanding of human gene regulation and complex diseases, and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in...
7.
Kuderna L, Gao H, Janiak M, Kuhlwilm M, Orkin J, Bataillon T, et al.
Science
. 2023 Jun;
380(6648):906-913.
PMID: 37262161
The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of...
8.
Gao H, Hamp T, Ede J, Schraiber J, McRae J, Singer-Berk M, et al.
Science
. 2023 Jun;
380(6648):eabn8153.
PMID: 37262156
Personalized genome sequencing has revealed millions of genetic differences between individuals, but our understanding of their clinical relevance remains largely incomplete. To systematically decipher the effects of human genetic variants,...
9.
Gao H, Hamp T, Ede J, Schraiber J, McRae J, Singer-Berk M, et al.
bioRxiv
. 2023 May;
PMID: 37205491
One Sentence Summary: Deep learning classifier trained on 4.3 million common primate missense variants predicts variant pathogenicity in humans.
10.
Storer J, Walker J, Rockwell C, Mores G, Beckstrom T, Orkin J, et al.
Genes (Basel)
. 2022 Apr;
13(4).
PMID: 35456378
Capuchins are platyrrhines (monkeys found in the Americas) within the Cebidae family. For most of their taxonomic history, the two main morphological types of capuchins, gracile (untufted) and robust (tufted),...