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Joseph C Chen

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Articles 45
Citations 685
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Recent Articles
31.
Chen J, Collins T
J Med Syst . 2012 May; 36(6):3851-60. PMID: 22562667
A well-managed healthcare system improves the quality of the patient experience. However, many small healthcare clinics have suboptimal systems for scheduling and locating patients and medical staff, delaying the relay...
32.
Fields A, Navarrete C, Zare A, Huang Z, Mostafavi M, Lewis J, et al.
Mol Microbiol . 2012 May; 84(5):892-920. PMID: 22553970
Although diminutive in size, bacteria possess highly diverse and spatially confined cellular structures. Two related alphaproteobacteria, Sinorhizobium meliloti and Caulobacter crescentus, serve as models for investigating the genetic basis of...
33.
Curtis P, Quardokus E, Lawler M, Guo X, Klein D, Chen J, et al.
Mol Microbiol . 2012 Apr; 84(4):712-35. PMID: 22512778
In the differentiating alphaproteobacterium Caulobacter crescentus, organelle synthesis at cell poles is critical to forming different progeny after cell division. Co-ordination of polar organelle synthesis, including pili and holdfast, and...
34.
Ho T, Santora K, Chen J, Frankshun A, Bagnell C
Bone . 2011 Mar; 48(6):1346-53. PMID: 21419242
Rheumatoid arthritis (RA) is characterized by joint inflammation and bone destruction. The receptor activator of nuclear factor-kappa B ligand (RANKL)-osteoprotegerin (OPG) system is important for maintaining the balance between bone...
35.
Chen J, Frankshun A, Wiley A, Miller D, Welch K, Ho T, et al.
Reproduction . 2011 Feb; 141(5):675-83. PMID: 21317299
Lactocrine communication of milk-borne bioactive factors (MbFs) from mother to offspring through nursing can affect neonatal development with lasting consequences. Relaxin (RLX), a lactocrine-active peptide found in porcine colostrum, stimulates...
36.
Arellano B, Ortiz J, Manzano J, Chen J
Appl Environ Microbiol . 2010 Mar; 76(9):3004-14. PMID: 20190087
Caulobacter crescentus, which thrives in freshwater environments with low nutrient levels, serves as a model system for studying bacterial cell cycle regulation and organelle development. We examined its ability to...
37.
Chen J, Wiley A, Ho T, Frankshun A, Hord K, Bartol F, et al.
Reproduction . 2009 Dec; 139(3):623-30. PMID: 20032211
Disruption of estrogen-sensitive, estrogen receptor (ER)-dependent events during porcine uterine development between birth (postnatal day=PND 0) and PND 14 affects patterns of uterine morphoregulatory gene expression in the neonate with...
38.
Chen J, Wiley A, Kauffold J, Wahner M, Bartol F, Bagnell C
Ann N Y Acad Sci . 2009 May; 1160:188-9. PMID: 19416184
The mycotoxin zearalenone (ZEA) is a selective estrogen receptor modulator that can contaminate cereal feeds and lead to reproductive disorders. To determine effects of perinatal ZEA exposure on uterine expression...
39.
Chen J, Stephens C
Curr Biol . 2007 Mar; 17(6):R203-6. PMID: 17371757
Recent advances in understanding bacterial cell-cycle regulation suggest circuit control mechanisms that operate analogously to those in the eukaryotic cell cycle.
40.
Chen J, Hottes A, McAdams H, McGrath P, Viollier P, Shapiro L
EMBO J . 2006 Jan; 25(2):377-86. PMID: 16395329
We demonstrate that successive cleavage events involving regulated intramembrane proteolysis (Rip) occur as a function of time during the Caulobacter cell cycle. The proteolytic substrate PodJ(L) is a polar factor...