Joseph C Burns
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Explore the profile of Joseph C Burns including associated specialties, affiliations and a list of published articles.
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20
Citations
944
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Recent Articles
1.
Sellon J, So K, DArcangelo A, Cancelarich S, Drummond M, Slade P, et al.
Front Mol Neurosci
. 2024 Jul;
17:1376128.
PMID: 38952419
Deafness-causing deficiencies in () have been addressed preclinically using dual adeno-associated virus (AAV)-based approaches. However, timing of transduction, recombination of mRNA, and protein expression with dual hybrid AAV methods methods...
2.
Kolla L, Kelly M, Mann Z, Anaya-Rocha A, Ellis K, Lemons A, et al.
Nat Commun
. 2020 May;
11(1):2389.
PMID: 32404924
Mammalian hearing requires the development of the organ of Corti, a sensory epithelium comprising unique cell types. The limited number of each of these cell types, combined with their close...
3.
McInturff S, Burns J, Kelley M
Biol Open
. 2018 Nov;
7(11).
PMID: 30455179
The utricle of the inner ear, a vestibular sensory structure that mediates perception of linear acceleration, is comprised of two morphologically and physiologically distinct types of mechanosensory hair cells, referred...
4.
Sun S, Babola T, Pregernig G, So K, Nguyen M, Su S, et al.
Cell
. 2018 Aug;
174(5):1247-1263.e15.
PMID: 30078710
Type I spiral ganglion neurons (SGNs) transmit sound information from cochlear hair cells to the CNS. Using transcriptome analysis of thousands of single neurons, we demonstrate that murine type I...
5.
Honda K, Kim S, Kelly M, Burns J, Constance L, Li X, et al.
Elife
. 2017 Oct;
6.
PMID: 28994389
Mutations of are a common cause of hearing loss associated with enlargement of the endolymphatic sac (EES). expression in the developing mouse endolymphatic sac is required for acquisition of normal...
6.
Burns J, Stone J
Semin Cell Dev Biol
. 2016 Nov;
65:96-105.
PMID: 27864084
Vestibular sensation is essential for gaze stabilization, balance, and perception of gravity. The vestibular receptors in mammals, Type I and Type II hair cells, are located in five small organs...
7.
Burns J, Kelly M, Hoa M, Morell R, Kelley M
Nat Commun
. 2015 Oct;
6:8557.
PMID: 26469390
In the inner ear, cochlear and vestibular sensory epithelia utilize grossly similar cell types to transduce different stimuli: sound and acceleration. Each individual sensory epithelium is composed of highly heterogeneous...
8.
Burns J, Corwin J
J Neurosci
. 2014 Jan;
34(5):1998-2011.
PMID: 24478379
Sensory hair cell (HC) loss is a major cause of permanent hearing and balance impairments for humans and other mammals. Yet, fish, amphibians, reptiles, and birds readily replace HCs and...
9.
Burns J, Corwin J
Hear Res
. 2013 Jan;
297:52-67.
PMID: 23333259
Hearing and balance deficits often affect humans and other mammals permanently, because their ears stop producing hair cells within a few days after birth. But production occurs throughout life in...
10.
Burns J, Collado M, Oliver E, Corwin J
J Comp Neurol
. 2012 Nov;
521(6):1430-48.
PMID: 23124808
Sensory hair cell losses lead to hearing and balance deficits that are permanent for mammals, but temporary for nonmammals because supporting cells in their ears give rise to replacement hair...