Josef Saltz
Overview
Explore the profile of Josef Saltz including associated specialties, affiliations and a list of published articles.
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Articles
2
Citations
64
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0
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Recent Articles
1.
A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion
Sharma J, Du M, Wong E, Mutyam V, Li Y, Chen J, et al.
Nat Commun
. 2021 Jul;
12(1):4358.
PMID: 34272367
Premature termination codons (PTCs) prevent translation of a full-length protein and trigger nonsense-mediated mRNA decay (NMD). Nonsense suppression (also termed readthrough) therapy restores protein function by selectively suppressing translation termination...
2.
Liang F, Shang H, Jordan N, Wong E, Mercadante D, Saltz J, et al.
SLAS Technol
. 2017 Apr;
22(3):315-324.
PMID: 28376702
Cystic fibrosis (CF) is a hereditary disease caused by mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR). A large number of nearly 2000 reported mutations,...