Josef Altenbuchner
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Explore the profile of Josef Altenbuchner including associated specialties, affiliations and a list of published articles.
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63
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973
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Recent Articles
1.
Aguilar Suarez R, Kohlstedt M, Oktem A, Neef J, Wu Y, Ikeda K, et al.
ACS Synth Biol
. 2024 Jul;
13(7):2199-2214.
PMID: 38981062
The Gram-positive bacterium is extensively used in the industry for the secretory production of proteins with commercial value. To further improve its performance, this microbe has been the subject of...
2.
Jasilionis A, Plotka M, Wang L, Dorawa S, Lange J, Watzlawick H, et al.
Protein Sci
. 2023 Feb;
32(3):e4585.
PMID: 36721347
Bacteriophages encode a wide variety of cell wall disrupting enzymes that aid the viral escape in the final stages of infection. These lytic enzymes have accumulated notable interest due to...
3.
Dobruchowska J, Bjornsdottir B, Fridjonsson O, Altenbuchner J, Watzlawick H, Gerwig G, et al.
Front Plant Sci
. 2022 Oct;
13:981602.
PMID: 36204061
Alginate (alginic acid) is a linear polysaccharide, wherein (1→4)-linked β-D-mannuronic acid and its C5 epimer, α-L-guluronic acid, are arranged in varying sequences. Alginate lyases catalyze the depolymerization of alginate, thereby...
4.
Michalik S, Reder A, Richts B, Fasshauer P, Mader U, Pedreira T, et al.
ACS Synth Biol
. 2021 Sep;
10(10):2767-2771.
PMID: 34587446
To better understand cellular life, it is essential to decipher the contribution of individual components and their interactions. Minimal genomes are an important tool to investigate these interactions. Here, we...
5.
Siebert D, Altenbuchner J, Blombach B
Front Bioeng Biotechnol
. 2021 Aug;
9:704681.
PMID: 34395409
Dynamic control of gene expression mainly relies on inducible systems, which require supplementation of (costly) inducer molecules. In contrast, synthetic regulatory circuits, which allow the timed shutdown of gene expression,...
6.
Freitag-Pohl S, Jasilionis A, Hakansson M, Svensson L, Kovacic R, Welin M, et al.
Acta Crystallogr D Struct Biol
. 2019 Nov;
75(Pt 11):1028-1039.
PMID: 31692476
As part of the Virus-X Consortium that aims to identify and characterize novel proteins and enzymes from bacteriophages and archaeal viruses, the genes of the putative lytic proteins XepA from...
7.
Watzlawick H, Altenbuchner J
AMB Express
. 2019 Oct;
9(1):158.
PMID: 31571017
The ganA gene from Bacillus subtilis encoding a β-galactosidase for degradation of the galactomannan was integrated in different loci of the B. subtilis chromosome employing the CRISPR/Cas9 system. Hereby a...
8.
Geissler M, Kuhle I, Heravi K, Altenbuchner J, Henkel M, Hausmann R
AMB Express
. 2019 Jun;
9(1):84.
PMID: 31190306
Strain engineering is often a method of choice towards increasing the yields of the biosurfactant surfactin which is naturally synthesized by many Bacillus spp., most notably Bacillus subtilis. In the...
9.
Heravi K, Watzlawick H, Altenbuchner J
J Bacteriol
. 2019 May;
201(15).
PMID: 31138628
is a heterotrophic soil bacterium that hydrolyzes different polysaccharides mainly found in the decomposed plants. These carbohydrates are mainly cellulose, hemicellulose, and the raffinose family of oligosaccharides (RFOs). RFOs are...
10.
Heravi K, Manzoor I, Watzlawick H, de Jong A, Kuipers O, Altenbuchner J
J Bacteriol
. 2019 Feb;
201(9).
PMID: 30782637
phosphorylates sugars during or after their transport into the cell. Perturbation in the conversion of intracellular phosphosugars to the central carbon metabolites and accumulation of phosphosugars can impose stress on...