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Josee Guindon

Explore the profile of Josee Guindon including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 1179
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Recent Articles
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Guindon J, Morgan D
J Pharmacol Exp Ther . 2024 Oct; 391(2):152-153. PMID: 39424315
No abstract available.
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Barnes R, Blanton H, Dancel C, Castro-Piedras I, Rorabaugh B, Morgan D, et al.
J Pharmacol Exp Ther . 2024 Jun; 391(2):258-271. PMID: 38936979
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy treatment, routinely manifesting as increased pain sensitivity (allodynia) in distal extremities. Despite its prevalence, effective treatment options are limited....
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Barnes R, Banjara S, McHann M, Almodovar S, Henderson-Redmond A, Morgan D, et al.
J Pharmacol Exp Ther . 2023 Dec; 388(2):655-669. PMID: 38129125
Inflammatory pain is caused by tissue hypersensitization and is a component of rheumatic diseases, frequently causing chronic pain. Current guidelines use a multimodal approach to pain and sociocultural changes have...
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Rorabaugh B, Guindon J, Morgan D
J Pharmacol Exp Ther . 2023 Sep; 387(3):265-276. PMID: 37739804
Cardiovascular disease represents a leading cause of death, morbidity, and societal economic burden. The prevalence of cannabis use has significantly increased due to legalization and an increased societal acceptance of...
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Singh S, Guindon J, Mody P, Ashworth G, Kopel J, Chilakapati S, et al.
Mol Pain . 2023 Sep; 19:17448069231203090. PMID: 37684099
Chronic pain is one of the most common, costly, and potentially debilitating health issues facing older adults, with attributable costs exceeding $600 billion annually. The prevalence of pain in humans...
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Lulek C, Maulik M, Mitra S, Guindon J, Morgan D, Henderson-Redmond A
Psychopharmacology (Berl) . 2023 Jul; 240(9):1987-2003. PMID: 37516707
Cannabinoids are increasingly used to alleviate pain; however, tolerance to their antinociceptive effects, including those of delta-9-tetrahydrocannabinol (Δ-THC), may limit their therapeutic utility. With more women than men using medical...
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Piscura M, Henderson-Redmond A, Barnes R, Mitra S, Guindon J, Morgan D
Biochem Pharmacol . 2023 Jun; 214:115665. PMID: 37348821
Cannabis has been used recreationally and medically for centuries, yet research into understanding the mechanisms of its therapeutic effects has only recently garnered more attention. There is evidence to support...
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Piscura M, Sepulveda D, Maulik M, Guindon J, Henderson-Redmond A, Morgan D
J Pharmacol Exp Ther . 2023 Jan; 385(1):17-34. PMID: 36669876
Tolerance to compounds that target G protein-coupled receptors (GPCRs), such as the cannabinoid type-1 receptor (CBR), is in part facilitated by receptor desensitization. Processes that mediate CBR desensitization include phosphorylation...
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Blanton H, McHann M, De Selle H, Dancel C, Redondo J, Molehin D, et al.
Front Pharmacol . 2022 Mar; 13:823132. PMID: 35242036
Cannabinoid-based therapies are increasingly being used by cancer patients to treat chemotherapy-induced nausea and vomiting. Recently, cannabinoids have gained increased attention for their effects on cancer growth. Indeed, the effect...