Jose R Lopez-Lopez
Overview
Explore the profile of Jose R Lopez-Lopez including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
286
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Recent Articles
1.
Peraza D, Benito-Salamanca L, Moreno-Estar S, Alonso E, Lopez-Lopez J, Perez-Garcia M, et al.
Front Physiol
. 2024 Nov;
15:1487775.
PMID: 39605858
Introduction: Coronary artery disease (CAD) is the foremost single cause of mortality and disability globally. Patients with type 2 diabetes (T2DM) have a higher incidence of CAD, and poorer prognosis....
2.
Daghbouche-Rubio N, Alvarez-Miguel I, Flores V, Rojo-Mencia J, Navedo M, Nieves-Citron M, et al.
Function (Oxf)
. 2024 Sep;
5(6).
PMID: 39322240
Essential hypertension (HT) is a highly prevalent cardiovascular disease of unclear physiopathology. Pharmacological studies suggest that purinergic P2Y6 receptors (P2ry6) play important roles in cardiovascular function and may contribute to...
3.
Serrano-Lorenzo P, Gobelli D, Garrido-Moraga R, Esteban-Amo M, Lopez-Lopez J, Orduna A, et al.
PLoS One
. 2023 Sep;
18(9):e0291442.
PMID: 37725617
Increasing evidence demonstrate that the electron transfer chain plays a critical role in controlling the effector functions of macrophages. In this work, we have generated a Ndufs4-/- murine macrophage cell...
4.
Serna J, Peraza D, Moreno-Estar S, Saez J, Gobelli D, Simarro M, et al.
J Cell Physiol
. 2023 Feb;
238(5):976-991.
PMID: 36852591
Voltage-dependent potassium channel Kv1.3 plays a key role on T-cell activation; however, lack of reliable antibodies has prevented its accurate detection under endogenous circumstances. To overcome this limitation, we created...
5.
Cazana-Perez V, Cidad P, Navarro-Gonzalez J, Rojo-Mencia J, Jaisser F, Lopez-Lopez J, et al.
Function (Oxf)
. 2022 Mar;
2(1):zqaa036.
PMID: 35330975
Chronic kidney disease (CKD) significantly increases cardiovascular risk. In advanced CKD stages, accumulation of toxic circulating metabolites and mineral metabolism alterations triggers vascular calcification, characterized by vascular smooth muscle cell...
6.
Arevalo-Martinez M, Cidad P, Moreno-Estar S, Fernandez M, Albinsson S, Cozar-Castellano I, et al.
Mol Metab
. 2021 Jul;
53:101306.
PMID: 34298200
Objectives: Restenosis after vessel angioplasty due to dedifferentiation of the vascular smooth muscle cells (VSMCs) limits the success of surgical treatment of vascular occlusions. Type 2 diabetes (T2DM) has a...
7.
Cidad P, Alonso E, Arevalo-Martinez M, Calvo E, de la Fuente M, Perez-Garcia M, et al.
J Cell Physiol
. 2020 Nov;
236(6):4330-4347.
PMID: 33230847
The voltage-dependent potassium channel Kv1.3 has been implicated in proliferation in many cell types, based on the observation that Kv1.3 blockers inhibited proliferation. By modulating membrane potential, cell volume, and/or...
8.
Arevalo-Martinez M, Cidad P, Garcia-Mateo N, Moreno-Estar S, Serna J, Fernandez M, et al.
Arterioscler Thromb Vasc Biol
. 2019 Oct;
39(12):e273-e286.
PMID: 31597447
Objective: We have previously described that changes in the expression of Kv channels associate to phenotypic modulation (PM), so that Kv1.3/Kv1.5 ratio is a landmark of vascular smooth muscle cells...
9.
Cazana-Perez V, Cidad P, Donate-Correa J, Martin-Nunez E, Lopez-Lopez J, Perez-Garcia M, et al.
Front Physiol
. 2018 Feb;
9:89.
PMID: 29483881
Patients with chronic kidney disease (CKD) have a markedly increased incidence of cardiovascular disease (CVD). The high concentration of circulating uremic toxins and alterations in mineral metabolism and hormone levels...
10.
Lopez-Lopez J, Cidad P, Perez-Garcia M
Microcirculation
. 2017 Nov;
25(1).
PMID: 29110368
Kv channels are present in virtually all VSMCs and strongly influence contractile responses. However, they are also instrumental in the proliferative, migratory, and secretory functions of synthetic, dedifferentiated VSMCs upon...